日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis

人乳头瘤病毒介导的 DNA 损伤感知和修复抑制导致皮肤致癌

Martin Hufbauer, James Cooke, Gijsbertus T J van der Horst, Herbert Pfister, Alan Storey, Baki Akgül

Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase

β-HPV5 E6 抵抗紫外线诱导的细胞凋亡涉及通过募集 HERC1 泛素连接酶靶向活化的 BAK 进行蛋白水解

Amy Holloway, Mark Simmonds, Abul Azad, Joanna L Fox, Alan Storey

Chk1 activity is required for BAK multimerization in association with PUMA during mitochondrial apoptosis

在线粒体凋亡过程中,Chk1 活性是 BAK 多聚化与 PUMA 结合所必需的

Abul Azad, Alan Storey

BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove

BAK 疏水沟中带负电荷的残基可抑制 BAK 多聚化导致的细胞凋亡,但不抑制 bid 结合

Abul Azad, Alan Storey

Expression of betapapillomavirus oncogenes increases the number of keratinocytes with stem cell-like properties

β乳头瘤病毒致癌基因的表达增加了具有干细胞样特性的角质形成细胞的数量

Martin Hufbauer, Adrian Biddle, Cinzia Borgogna, Marisa Gariglio, John Doorbar, Alan Storey, Herbert Pfister, Ian Mackenzie, Baki Akgül

Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis

通过抑制磷酸化阻断BAK疏水沟来调节细胞凋亡

Abul Azad, Joanna Fox, Sabrina Leverrier, Alan Storey

TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development

TTBK2激酶底物特异性以及脊髓小脑性共济失调致病突变对其表达、活性、定位和发育的影响

Bouskila, Michale; Esoof, Noor; Gay, Laurie; Fang, Emily H; Deak, Maria; Begley, Michael J; Cantley, Lewis C; Prescott, Alan; Storey, Kate G; Alessi, Dario R

Tyrosine dephosphorylation is required for Bak activation in apoptosis

酪氨酸去磷酸化是细胞凋亡中BAK激活的必要条件

Joanna L Fox, Ferina Ismail, Abul Azad, Nicola Ternette, Sabrina Leverrier, Mariola J Edelmann, Benedikt M Kessler, Irene M Leigh, Sarah Jackson, Alan Storey

Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen

基底膜 VII 型胶原蛋白缺失导致皮肤鳞状细胞癌侵袭性增强

Vera L Martins, Jashmin J Vyas, Mei Chen, Karin Purdie, Charles A Mein, Andrew P South, Alan Storey, John A McGrath, Edel A O'Toole

HPV8 early genes modulate differentiation and cell cycle of primary human adult keratinocytes

HPV8 早期基因调节人类成人原代角质形成细胞的分化和细胞周期

Baki Akgül, Lucy Ghali, Derek Davies, Herbert Pfister, Irene M Leigh, Alan Storey