Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs
应用人源化小鼠模型模拟细胞色素P450介导的药物代谢,预测肽类药物与小分子药物之间的药物相互作用
期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1016/j.dmd.2025.100153
Kapelyukh, Yury; Gabel-Jensen, Charlotte; MacLeod, Alastaire Kenneth; Daniel Coquelin, Kevin-Sebastien; Stojanovski, Laste; Frame, Laura; Tavendale, Amy; Henderson, Colin J; Read, Kevin D; Wolf, Charles Roland; Säll, Carolina