日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel derivatives of anaplastic lymphoma kinase inhibitors: Synthesis, radiolabeling, and preliminary biological studies of fluoroethyl analogues of crizotinib, alectinib, and ceritinib

新型间变性淋巴瘤激酶抑制剂衍生物:克唑替尼、阿来替尼和色瑞替尼氟乙基类似物的合成、放射性标记和初步生物学研究

Radaram, Bhasker; Pisaneschi, Federica; Rao, Yi; Yang, Ping; Piwnica-Worms, David; Alauddin, Mian M

Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer

靶向分子遗传成像和配体导向治疗在侵袭性变异型前列腺癌中的应用

Ferrara, Fortunato; Staquicini, Daniela I; Driessen, Wouter H P; D'Angelo, Sara; Dobroff, Andrey S; Barry, Marc; Lomo, Lesley C; Staquicini, Fernanda I; Cardó-Vila, Marina; Soghomonyan, Suren; Alauddin, Mian M; Flores, Leo G 2nd; Arap, Marco A; Lauer, Richard C; Mathew, Paul; Efstathiou, Eleni; Aparicio, Ana M; Troncoso, Patricia; Navone, Nora M; Logothetis, Christopher J; Marchiò, Serena; Gelovani, Juri G; Sidman, Richard L; Pasqualini, Renata; Arap, Wadih

Synthesis of a [(18)F]-labeled ceritinib analogue for positron emission tomography of anaplastic lymphoma kinase, a receptor tyrosine kinase, in lung cancer

合成[(18)F]标记的色瑞替尼类似物用于肺癌中间变性淋巴瘤激酶(一种受体酪氨酸激酶)的正电子发射断层扫描

Perera, Sandun; Piwnica-Worms, David; Alauddin, Mian M

Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain

用于脑表观遗传调控PET成像的新型组蛋白去乙酰化酶IIa类选择性底物放射性示踪剂

Bonomi, Robin; Mukhopadhyay, Uday; Shavrin, Aleksandr; Yeh, Hsien-Hsien; Majhi, Anjoy; Dewage, Sajeewa W; Najjar, Amer; Lu, Xin; Cisneros, G Andrés; Tong, William P; Alauddin, Mian M; Liu, Ren-Shuan; Mangner, Thomas J; Turkman, Nashaat; Gelovani, Juri G

Optimization of precursor synthesis, formulation and stability of 1'-[18F]fluoroethyl-β-D-lactose ([18F]FEL) for preclinical studies in detection of pancreatic cancer

优化1'-[18F]氟乙基-β-D-乳糖([18F]FEL)前体的合成、配方和稳定性,用于胰腺癌检测的临床前研究

Paolillo, Vincenzo; De Palatis, Louis; Alauddin, Mian M

Preliminary evaluation of 1'-[(18)F]fluoroethyl-β-D-lactose ([(18)F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts

1'-[(18)F]氟乙基-β-D-乳糖([(18)F]FEL)在裸鼠原位异种移植胰腺癌检测中的初步评价

Arumugam, Thiruvengadam; Paolillo, Vincenzo; Young, Daniel; Wen, XiaoXia; Logsdon, Craig D; De Palatis, Louis; Alauddin, Mian M

An investigation on stereospecific fluorination at the 2'-arabino-position of a pyrimidine nucleoside: radiosynthesis of 2'-deoxy-2'-[(18)F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil

对嘧啶核苷2'-阿拉伯糖位立体选择性氟化的研究:2'-脱氧-2'-[(18)F]氟-5-甲基-1-β-D-阿拉伯呋喃糖基尿嘧啶的放射合成

Turkman, Nashaat; Paolillo, Vincenzo; Gelovani, Juri G; Alauddin, Mian M

Improved detection and measurement of low levels of [18F]fluoride metabolized from [18F]-labeled pyrimidine nucleoside analogues in biological samples

改进对生物样品中由[18F]标记的嘧啶核苷类似物代谢产生的低浓度[18F]氟化物的检测和测量

Paolillo, Vincenzo; Yeh, Hsin Hsien; Mukhopadhyay, Uday; Gelovani, Juri G; Alauddin, Mian M

Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives.

氟化大麻素 CB2 受体配体:2-氧代喹啉衍生物的合成及体外结合特性

Turkman Nashaat, Shavrin Aleksander, Ivanov Roman A, Rabinovich Brian, Volgin Andrei, Gelovani Juri G, Alauddin Mian M

Radiosynthesis and initial in vitro evaluation of [18F]F-PEG6-IPQA--a novel PET radiotracer for imaging EGFR expression-activity in lung carcinomas

[18F]F-PEG6-IPQA 的放射合成及初步体外评价——一种用于肺癌中 EGFR 表达活性成像的新型 PET 放射性示踪剂

Pal, Ashutosh; Balatoni, Julius A; Mukhopadhyay, Uday; Ogawa, Kazuma; Gonzalez-Lepera, Carlos; Shavrin, Aleksandr; Volgin, Andrei; Tong, William; Alauddin, Mian M; Gelovani, Juri G