FGFR3-induced Y158 PARP1 phosphorylation promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer models
在乳腺癌模型中，FGFR3诱导的Y158 PARP1磷酸化通过BRG1/MRE11介导的DNA修复促进PARP抑制剂耐药性
期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI173757
Chen, Mei-Kuang; Yamaguchi, Hirohito; Gao, Yuan; Xia, Weiya; Chang, Jeffrey T; Hsiao, Yu-Chun; Shegute, Tewodros W; Lin, Zong-Shin; Wu, Chen-Shiou; Wang, Yu-Han; Litton, Jennifer K; Ding, Qingqing; Wei, Yongkun; Chu, Yu-Yi; Meric-Bernstam, Funda; Piwnica-Worms, Helen; Arun, Banu; Rodon Ahnert, Jordi; Liu, Jinsong; Yao, Jun; Chang, Wei-Chao; Wang, Hung-Ling; Tapia, Coya; Albarracin, Constance T; Keyomarsi, Khandan; Wang, Shao-Chun; Wang, Ying-Nai; Hortobagyi, Gabriel N; Lin, Chunru; Yang, Liuqing; Yu, Dihua; Hung, Mien-Chie
FGFR3
肿瘤
PARP1
肿瘤免疫
信号转导
乳腺癌
PARP
磷酸化
