日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The deacetylase NagA mediates the remodeling and recycling of peptidoglycan-derived amino sugars in mycobacteria

脱乙酰酶NagA介导分枝杆菌中肽聚糖衍生的氨基糖的重塑和再利用

Guy, Collette S; Cooper, Charlotte; Karlikowska, Magdalena; Harrison, James; Singh, Albel; Servín-González, Luis Steven; Evans, Caroline A; Bakker, Saskia E; Bottrill, Andrew; Bhatt, Apoorva; Mesnage, Stéphane; Besra, Gurdyal S; Fullam, Elizabeth

MmpL12 transports lipooligosaccharides and impacts virulence in Mycobacterium marinum

MmpL12 运输脂寡糖并影响海分枝杆菌的毒力

Bailo, Rebeca; Kumar, C M Santosh; Singh, Albel; Lund, Peter A; Bavro, Vassiliy N; Bhatt, Apoorva

VadK, a Non-Canonical Kinase that Regulates the Methylcitrate Cycle and is Essential for Mycobacterium tuberculosis Virulence

VadK是一种非经典激酶,它调控甲基柠檬酸循环,对结核分枝杆菌的毒力至关重要。

Pascoe, Jordan; Newcombe, Jane; Mendoza, Jessica; Birua, Shalini; Mendum, Tom A; Anand, Kushi; Singh, Albel; Sinha, Amitava; Papavinasasundaram, Kadamba; Bhatt, Apoorva; Larrouy-Maumus, Gerald; Singh, Amit; Goulding, Celia W; Beste, Dany Jv

The mycobacterial desaturase DesA2 is associated with mycolic acid biosynthesis

分枝杆菌去饱和酶DesA2与分枝菌酸的生物合成有关。

Bailo, Rebeca; Radhakrishnan, Anjana; Singh, Albel; Nakaya, Makoto; Fujiwara, Nagatoshi; Bhatt, Apoorva

NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo

NSC19723 是一种硫乙酰酮类苯甲醛缩氨基硫脲,可提高结核病药物在体内和体外的疗效

Padam Singh, Srishti Rawat, Ashish Kumar Agrahari, Manisha Singh, Saurabh Chugh, Sudagar Gurcha, Albel Singh, Katherine Abrahams, Gurdyal S Besra, Shailendra Asthana, Diwan S Rawat, Ramandeep Singh

Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

对耻垢分枝杆菌转运蛋白 UspABC 进行生化和表型表征

Karlikowska, Magdalena; Singh, Albel; Bhatt, Apoorva; Ott, Sascha; Bottrill, Andrew R; Besra, Gurdyal S; Fullam, Elizabeth

Insights into the ancestry evolution of the Mycobacterium tuberculosis complex from analysis of Mycobacterium riyadhense

通过对利雅得分枝杆菌的分析了解结核分枝杆菌复合体的祖先进化

Qingtian Guan, Musa Garbati, Sara Mfarrej, Talal AlMutairi, Thomas Laval, Albel Singh, Shamsudeen Fagbo, Alicia Smyth, John A Browne, Muhammad Amin urRahman, Alya Alruwaili, Anwar Hoosen, Conor J Meehan, Chie Nakajima, Yasuhiko Suzuki, Caroline Demangel, Apoorva Bhatt, Stephen V Gordon, Faisal AlAsm

Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production

与重症结核病相关的结核分枝杆菌能够逃避胞质监视系统并调节IL-1β的产生。

Jeremy Sousa # ,Baltazar Cá # ,Ana Raquel Maceiras ,Luisa Simões-Costa ,Kaori L Fonseca ,Ana Isabel Fernandes ,Angélica Ramos ,Teresa Carvalho ,Leandro Barros ,Carlos Magalhães ,Álvaro Chiner-Oms ,Henrique Machado ,Maria Isabel Veiga ,Albel Singh ,Rui Pereira ,António Amorim ,Jorge Vieira ,Cristina P Vieira ,Apoorva Bhatt ,Fernando Rodrigues ,Pedro N S Rodrigues ,Sebastien Gagneux ,António Gil Castro ,João Tiago Guimarães ,Helder Novais Bastos ,Nuno S Osório ,Iñaki Comas ,Margarida Saraiva

The mycolic acid reductase Rv2509 has distinct structural motifs and is essential for growth in slow-growing mycobacteria

分枝酸还原酶 Rv2509 具有独特的结构基序,对于生长缓慢的分枝杆菌的生长至关重要

Asma Javid, Charlotte Cooper, Albel Singh, Steffen Schindler, Milena Hänisch, Robert L Marshall, Rainer Kalscheuer, Vassiliy N Bavro, Apoorva Bhatt

Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

转座子文库鉴定出参与牛分枝杆菌卡介苗体内传代过程中动态相互作用的新型基因,这些基因对于卡介苗在牛体内持续存在至关重要。

Mendum, Tom A; Chandran, Aneesh; Williams, Kerstin; Vordermeier, H Martin; Villarreal-Ramos, Bernardo; Wu, H; Singh, Albel; Smith, Alex A; Butler, Rachel E; Prasad, Aravind; Bharti, Neeraj; Banerjee, Ruma; Kasibhatla, Sunitha M; Bhatt, Apoorva; Stewart, Graham R; McFadden, Johnjoe