A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers.
一种以吡咯并苯二氮卓类药物为有效载荷的人源化间变性淋巴瘤激酶（ALK）靶向抗体药物偶联物，在表达ALK的癌症中显示出疗效
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-62979-1
Guerra Alberto D, Matkar Smita, Acholla Christina, Casey Colleen, Li Grant, Mazzeschi Martina, Patel Khushbu, Krytska Kateryna, Chen Chuan, Balyasny Skye, Kalna Joshua, Kamitsuka Paul, Gerelus Mark, Polkosnik Grace, Groff David, Mukherje Apratim, Adams Cynthia, Witek Gabriela, Hamilton Amber K, Martinez Daniel, Pogoriler Jennifer, Spear Timothy T, Li Yimei, Jung Piotr, Alvarado Diego, Lauriola Mattia, Maris John M, Wolpaw Adam J, Bosse Kristopher R, Dimitrov Dimiter, Mir Mustafa, Jelev Dontcho V, Mossé Yael P
