日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unspecific Peroxygenases-Catalyzed Oxidation of Pharmaceutical Compounds Considered Emerging Contaminants

非特异性过氧化酶催化的药物化合物氧化被认为是新兴污染物

Torres-Aguirre, Alina; López-López, Azucena; Avelar, Mayra; Alcalde, Miguel; Ayala, Marcela

Directed evolution of LaccID for cell surface proximity labeling and electron microscopy

LaccID的定向进化用于细胞表面邻近标记和电子显微镜

Lee, Song-Yi; Roh, Heegwang; Gonzalez-Perez, David; Mackey, Mason R; Hoces, Daniel; McLaughlin, Colleen N; Lin, Chang; Adams, Stephen R; Nguyen, Khanh; Kim, Keun-Young; Luginbuhl, David J; Luo, Liqun; Udeshi, Namrata D; Carr, Steven A; Hernández-López, Rogelio A; Ellisman, Mark H; Alcalde, Miguel; Ting, Alice Y

Synthesis of 19-Hydroxyarachidonic Acid by Fungal Peroxygenases: An Experimental and Computational Study

真菌过氧化酶合成19-羟基花生四烯酸:实验与计算研究

González-Benjumea, Alejandro; Martínez-Sugrañes, Mireia; Alcalde, Miguel; Romero, Elvira; Guallar, Víctor; Floor, Martin; Martínez, Angel T; Gutiérrez, Ana

Secondary Metabolites in Plants

植物次生代谢产物

Palazon, Javier; Alcalde, Miguel Angel

Stable and Promiscuous Galactose Oxidases Engineered by Directed Evolution, Atomistic Design, and Ancestral Sequence Reconstruction

通过定向进化、原子级设计和祖先序列重建技术构建的稳定且具有广泛底物特异性的半乳糖氧化酶

Keser, Merve; Mateljak, Ivan; Kittl, Roman; Ludwig, Roland; Risso, Valeria A; Sanchez-Ruiz, Jose M; Gonzalez-Perez, David; Alcalde, Miguel

Engineering the Tobacco Etch Virus Protease toward a Platform for Traceless Cleavage Using Distal Site Prediction and Smart Library Design

利用远端位点预测和智能文库设计,对烟草蚀纹病毒蛋白酶进行改造,构建无痕切割平台。

Bemelmans, Martijn P; Wetzel, Bach-Ngan; Neusius, Florian G; Tieves, Florian; Schwarz, Christian; Mateljak, Ivan; Świderek, Katarzyna; Moliner, Vicent; Alcalde, Miguel; Sieber, Volker

Enzyme Benchmarking with Polyethylene Furanoate Soluble Scaffolds for Directed Evolution of PEFases

利用聚呋喃甲酸乙二醇酯可溶性支架进行酶基准测试,以实现PEFase的定向进化

Dolz, Mikel; Monterrey, Dianelis T; Quartinello, Felice; de Santos, Patricia Gomez; Mateljak, Ivan; Pellis, Alessandro; Guebitz, Georg; Viña-González, Javier; Alcalde, Miguel

Structural Insights and Reaction Profile of a New Unspecific Peroxygenase from Marasmius wettsteinii Produced in a Tandem-Yeast Expression System

利用串联酵母表达系统对韦氏小球藻(Marasmius wettsteinii)中一种新型非特异性过氧化酶的结构解析和反应特性进行研究

Sánchez-Moreno, Israel; Fernandez-Garcia, Angela; Mateljak, Ivan; Gomez de Santos, Patricia; Hofrichter, Martin; Kellner, Harald; Sanz-Aparicio, Julia; Alcalde, Miguel

Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C-H Oxyfunctionalization Reactions

用于对映体发散型CH氧官能化反应的计算设计过氧化酶库

Gomez de Santos, Patricia; Mateljak, Ivan; Hoang, Manh Dat; Fleishman, Sarel J; Hollmann, Frank; Alcalde, Miguel

Genetic approaches in improving biotechnological production of taxanes: An update

利用遗传学方法改进紫杉烷类药物的生物技术生产:最新进展

Perez-Matas, Edgar; Hidalgo-Martinez, Diego; Escrich, Ainoa; Alcalde, Miguel Angel; Moyano, Elisabeth; Bonfill, Mercedes; Palazon, Javier