Alderwick Luke J相关文献与解析，生知库 | 链接生命科学的每一步

Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation.

结核分枝杆菌在生物膜生长过程中会改变细胞壁碳水化合物，同时减少补体激活

doi:10.1016/j.tcsw.2021.100065

Keating Thomas, Lethbridge Samuel, Allnutt Jon C, Hendon-Dunn Charlotte L, Thomas Stephen R, Alderwick Luke J, Taylor Stephen C, Bacon Joanna

细胞生物学

发表日期：2021

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Structure-based in silico approaches for drug discovery against Mycobacterium tuberculosis

基于结构的计算机模拟方法用于结核分枝杆菌药物发现

期刊:Computational and Structural Biotechnology Journal

影响因子:4.1

doi:10.1016/j.csbj.2021.06.034

Kingdon, Alexander D H; Alderwick, Luke J

发表日期：2021

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HIV Drugs Inhibit Transfer of Plasmids Carrying Extended-Spectrum β-Lactamase and Carbapenemase Genes

HIV药物抑制携带超广谱β-内酰胺酶和碳青霉烯酶基因的质粒转移

期刊:mBio

影响因子:4.7

doi:10.1128/mBio.03355-19

Buckner, Michelle M C; Ciusa, M Laura; Meek, Richard W; Moorey, Alice R; McCallum, Gregory E; Prentice, Emma L; Reid, Jeremy P; Alderwick, Luke J; Di Maio, Alessandro; Piddock, Laura J V

Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria

利用普雷斯特威克化学库筛选抑制分枝杆菌生长的药物

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0213713

Kanvatirth, Panchali; Jeeves, Rose E; Bacon, Joanna; Besra, Gurdyal S; Alderwick, Luke J

发表日期：2019

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AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

AftD 是一种 α1 → 5 阿拉伯呋喃糖基转移酶，参与分枝杆菌细胞壁核心的生物合成。

期刊:Cell Surface

影响因子:6.2

doi:10.1016/j.tcsw.2017.10.001

Alderwick, Luke J; Birch, Helen L; Krumbach, Karin; Bott, Michael; Eggeling, Lothar; Besra, Gurdyal S

细胞生物学

发表日期：2018

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The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis

谷氨酸棒状杆菌特有的Emb阿拉伯呋喃糖基转移酶在细胞壁阿拉伯聚糖生物合成的早期阶段聚合α(1→5)阿拉伯聚糖骨架。

期刊:Cell Surface

影响因子:6.2

doi:10.1016/j.tcsw.2018.06.003

Jankute, Monika; Alderwick, Luke J; Moorey, Alice R; Joe, Maju; Gurcha, Sudagar S; Eggeling, Lothar; Lowary, Todd L; Dell, Anne; Pang, Poh-Choo; Yang, Tiandi; Haslam, Stuart; Besra, Gurdyal S

细胞生物学

发表日期：2018

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Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach

利用整合的全细胞靶点方法鉴定和表征抗结核分枝杆菌的天冬氨酰tRNA合成酶抑制剂

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-018-31157-3

Soto, Ramón; Perez-Herran, Esther; Rodriguez, Beatriz; Duma, Bogdan M; Cacho-Izquierdo, Monica; Mendoza-Losana, Alfonso; Lelievre, Joel; Aguirre, David Barros; Ballell, Lluis; Cox, Liam R; Alderwick, Luke J; Besra, Gurdyal S

细胞生物学

发表日期：2018

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Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

分枝杆菌 AftB 基因的破坏导致脂阿拉伯甘露聚糖末端 β(1→2) 阿拉伯呋喃糖残基的完全丧失

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/acschembio.6b00898

Jankute, Monika; Alderwick, Luke J; Noack, Stephan; Veerapen, Natacha; Nigou, Jérôme; Besra, Gurdyal S

发表日期：2017

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Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis

Lcp1 是一种磷酸转移酶，负责将阿拉伯半乳聚糖连接到结核分枝杆菌中的肽聚糖上。

期刊:mBio

影响因子:4.7

doi:10.1128/mBio.00972-16

Harrison, James; Lloyd, Georgina; Joe, Maju; Lowary, Todd L; Reynolds, Edward; Walters-Morgan, Hannah; Bhatt, Apoorva; Lovering, Andrew; Besra, Gurdyal S; Alderwick, Luke J

发表日期：2016

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Enhanced immunogenicity of Mycobacterium bovis BCG through CRISPRi mediated depletion of AftC

通过 CRISPRi 介导的 AftC 耗竭增强牛分枝杆菌 BCG 的免疫原性

Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation.

结核分枝杆菌在生物膜生长过程中会改变细胞壁碳水化合物，同时减少补体激活

Structure-based in silico approaches for drug discovery against Mycobacterium tuberculosis

基于结构的计算机模拟方法用于结核分枝杆菌药物发现

HIV Drugs Inhibit Transfer of Plasmids Carrying Extended-Spectrum β-Lactamase and Carbapenemase Genes

HIV药物抑制携带超广谱β-内酰胺酶和碳青霉烯酶基因的质粒转移

Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria

利用普雷斯特威克化学库筛选抑制分枝杆菌生长的药物

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

AftD 是一种 α1 → 5 阿拉伯呋喃糖基转移酶，参与分枝杆菌细胞壁核心的生物合成。

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis

谷氨酸棒状杆菌特有的Emb阿拉伯呋喃糖基转移酶在细胞壁阿拉伯聚糖生物合成的早期阶段聚合α(1→5)阿拉伯聚糖骨架。

Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach

利用整合的全细胞靶点方法鉴定和表征抗结核分枝杆菌的天冬氨酰tRNA合成酶抑制剂

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

分枝杆菌 AftB 基因的破坏导致脂阿拉伯甘露聚糖末端 β(1→2) 阿拉伯呋喃糖残基的完全丧失

Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis

Lcp1 是一种磷酸转移酶，负责将阿拉伯半乳聚糖连接到结核分枝杆菌中的肽聚糖上。

Enhanced immunogenicity of Mycobacterium bovis BCG through CRISPRi mediated depletion of AftC

通过 CRISPRi 介导的 AftC 耗竭增强牛分枝杆菌 BCG 的免疫原性

Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation.

结核分枝杆菌在生物膜生长过程中会改变细胞壁碳水化合物，同时减少补体激活

Structure-based in silico approaches for drug discovery against Mycobacterium tuberculosis

基于结构的计算机模拟方法用于结核分枝杆菌药物发现

HIV Drugs Inhibit Transfer of Plasmids Carrying Extended-Spectrum β-Lactamase and Carbapenemase Genes

HIV药物抑制携带超广谱β-内酰胺酶和碳青霉烯酶基因的质粒转移

Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria

利用普雷斯特威克化学库筛选抑制分枝杆菌生长的药物

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

AftD 是一种 α1 → 5 阿拉伯呋喃糖基转移酶，参与分枝杆菌细胞壁核心的生物合成。

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis

谷氨酸棒状杆菌特有的Emb阿拉伯呋喃糖基转移酶在细胞壁阿拉伯聚糖生物合成的早期阶段聚合α(1→5)阿拉伯聚糖骨架。

Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach

利用整合的全细胞靶点方法鉴定和表征抗结核分枝杆菌的天冬氨酰tRNA合成酶抑制剂

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan

分枝杆菌 AftB 基因的破坏导致脂阿拉伯甘露聚糖末端 β(1→2) 阿拉伯呋喃糖残基的完全丧失

Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis

Lcp1 是一种磷酸转移酶，负责将阿拉伯半乳聚糖连接到结核分枝杆菌中的肽聚糖上。

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis