Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion
PDIA1 在肝细胞中的条件性消融揭示了其在 APOB 和 MTTP 折叠中对支持 VLDL 分泌的不可或缺的作用
期刊:Molecular Metabolism
影响因子:7
doi:10.1016/j.molmet.2024.101874
Zhouji Chen, Shiyu Wang, Anita Pottekat, Alec Duffey, Insook Jang, Benny H Chang, Jaehyung Cho, Brian N Finck, Nicholas O Davidson, Randal J Kaufman