Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease
在阿尔茨海默病的 APP/PS1 模型中，小胶质细胞铁输入基因 Slc11a2 的敲低会导致认知功能恶化，并以性别特异性的方式改变小胶质细胞的转录格局
期刊:Journal of Neuroinflammation
影响因子:9.3
doi:10.1186/s12974-024-03238-w
Katrina Volk Robertson, Alec S Rodriguez, Jean-Philippe Cartailler, Shristi Shrestha, Michael W Schleh, Kyle R Schroeder, Arianna M Valenti, Alec T Kramer, Fiona E Harrison, Alyssa H Hasty
