Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia
新型 2,6,9-三取代嘌呤衍生物的设计、合成、计算机模拟研究以及对 Bcr-Abl、BTK 和 FLT3-ITD 的抑制活性,作为治疗白血病的潜在药物
期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics14061294
Jeanluc Bertrand, Hana Dostálová, Vladimír Kryštof, Radek Jorda, Thalía Delgado, Alejandro Castro-Alvarez, Jaime Mella, David Cabezas, Mario Faúndez, Christian Espinosa-Bustos, Cristian O Salas