Chronic and acute LRRK2 silencing has no long-term behavioral effects, whereas wild-type and mutant LRRK2 overexpression induce motor and cognitive deficits and altered regulation of dopamine release
慢性和急性 LRRK2 沉默不会对行为产生长期影响，而野生型和突变型 LRRK2 过表达则会引起运动和认知障碍，并改变多巴胺释放的调节
期刊:Parkinsonism & Related Disorders
影响因子:3.1
doi:10.1016/j.parkreldis.2015.07.025
Mattia Volta, Stefano Cataldi, Dayne Beccano-Kelly, Lise Munsie, Igor Tatarnikov, Patrick Chou, Sabrina Bergeron, Emma Mitchell, Roscoe Lim, Jaskaran Khinda, Alejandro Lloret, C Frank Bennett, Carmela Paradiso, Michele Morari, Matthew J Farrer, Austen J Milnerwood
