日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of PIM Kinase in Tumor-Associated Macrophages Suppresses Inflammasome Activation and Sensitizes Prostate Cancer to Immunotherapy

抑制肿瘤相关巨噬细胞中的PIM激酶可抑制炎症小体激活并增强前列腺癌对免疫疗法的敏感性

Amber N Clements ,Andrea L Casillas ,Caitlyn E Flores ,Hope Liou ,Rachel K Toth ,Shailender S Chauhan ,Kai Sutterby ,Sachin Kumar Deshmukh ,Sharon Wu ,Joanne Xiu ,Alex Farrell ,Milan Radovich ,Chadi Nabhan ,Elisabeth I Heath ,Rana R McKay ,Noor Subah ,Sara Centuori ,Travis J Weeler ,Anne E Cress ,Gregory C Rogers ,Justin E Wilson ,Alejandro Recio-Boiles ,Noel A Warfel

Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors

Azenosertib 是一种强效且选择性的 WEE1 激酶抑制剂,对多种实体瘤具有广泛的抗肿瘤活性。

Jianhui Ma # ,Wen Liu # ,Jiali Li # ,Daehwan Kim ,Sangyub Kim ,Alexandra Levy ,Zhen Cai ,Kevin D Bunker ,Alejandro Recio-Boiles ,Jennifer M Segar ,Shiraj Sen ,Deborah B Doroshow ,Danielle Jandial ,Michael Rutgard ,Olivier Harismendy ,Stephan K Grant ,Ahmed A Samatar ,Kimberlee M Fischer ,Mark R Lackner