日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clonal tracing with somatic epimutations reveals dynamics of blood ageing

利用体细胞表观突变进行克隆追踪揭示血液衰老的动态过程

Michael Scherer # ,Indranil Singh # ,Martina Maria Braun # ,Chelsea Szu-Tu # ,Pedro Sanchez Sanchez ,Dominik Lindenhofer ,Niels Asger Jakobsen ,Verena Körber ,Michael Kardorff ,Lena Nitsch ,Pauline Kautz ,Julia Rühle ,Agostina Bianchi ,Luca Cozzuto ,Robert Frömel ,Sergi Beneyto-Calabuig ,Caleb Lareau ,Ansuman T Satpathy ,Renée Beekman ,Lars M Steinmetz ,Simon Raffel ,Leif S Ludwig ,Paresh Vyas ,Alejo Rodriguez-Fraticelli ,Lars Velten

Enhancing immunotherapy through PD-L1 upregulation: the promising combination of anti-PD-L1 plus mTOR inhibitors

通过上调PD-L1增强免疫疗法:抗PD-L1抑制剂联合mTOR抑制剂的前景广阔

Anna Hernández-Prat ,Alejo Rodriguez-Vida ,Laura Cardona ,Mengjuan Qin ,Oriol Arpí-Llucià ,Luis Soria-Jiménez ,Sílvia Menendez ,Fabricio Gerel Quimis ,Miguel Galindo ,Edurne Arriola ,Marta Salido ,Nuria Juanpere-Rodero ,Federico Rojo ,Aura Muntasell ,Joan Albanell ,Ana Rovira ,Joaquim Bellmunt

Bone metastases in advanced urothelial carcinoma patients receiving enfortumab vedotin: A Real-World study from the ARON-2(EV) project

接受恩福妥单抗治疗的晚期尿路上皮癌患者的骨转移:来自 ARON-2(EV) 项目的真实世界研究

Rizzo, Alessandro; Myint, Zin W; Ciccimarra, Francesco; Zgura, Anca; Matrana, Marc R; Büttner, Thomas; Kopecky, Jindrich; Vida, Alejo Rodriguez; Rizzo, Mimma; Fujita, Kazutoshi; Brunetti, Oronzo; Santini, Daniele; Park, Se Hoon; Formisano, Luigi; Poprach, Alexandr; Kucharz, Jakub; Comes, Maria Colomba; Bove, Samantha; Fanizzi, Annarita; Massafra, Raffaella; Cazzato, Gerardo; Monteiro, Fernando Sabino Marques; Mollica, Veronica; Massari, Francesco; Cerrillo, Javier Molina; Santoni, Matteo

Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGFβ) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors

转化生长因子-β (TGFβ) 抑制剂 SAR439459 作为单一疗法和与 cemiplimab 联合治疗晚期实体肿瘤患者的 I 期临床研究的生物标志物和药效学活性

Debbie Robbrecht, Jean-Jacques Grob, Oliver Bechter, Matteo Simonelli, Bernard Doger, Ivan Borbath, Marcus O Butler, Tina Cheng, Patricia Martin Romano, Elvire Pons-Tostivint, Massimo Di Nicola, Giuseppe Curigliano, Min-Hee Ryu, Alejo Rodriguez-Vida, Dirk Schadendorf, Elena Garralda, Giovanni Abbade

Somatic epimutations enable single-cell lineage tracing in native hematopoiesis across the murine and human lifespan

体细胞表观突变使得在小鼠和人类生命周期内进行原生造血的单细胞谱系追踪成为可能

Michael Scherer, Indranil Singh, Martina Braun, Chelsea Szu-Tu, Michael Kardorff, Julia Rühle, Robert Frömel, Sergi Beneyto-Calabuig, Simon Raffel, Alejo Rodriguez-Fraticelli, Lars Velten

Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity

Taz 保护造血干细胞免受因衰老而导致的 PU.1 活性下降

Kyung Mok Kim #, Anna Mura-Meszaros #, Marie Tollot #, Murali Shyam Krishnan, Marco Gründl, Laura Neubert, Marco Groth, Alejo Rodriguez-Fraticelli, Arthur Flohr Svendsen, Stefano Campaner, Nico Andreas, Thomas Kamradt, Steve Hoffmann, Fernando D Camargo, Florian H Heidel, Leonid V Bystrykh, Gerald d

Effectiveness of telesimulation for pediatric minimally invasive surgery essential skills training

远程模拟在儿科微创手术基本技能培训中的有效性

Falcioni, Alejandra Georgina; Yang, Hsien Chen; Maricic, Maximiliano Alejo; Rodriguez, Susana Patricia; Bailez, Maria Marcela

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

小鼠多能祖细胞 5 位于造血干细胞和祖细胞的界面

Pia Sommerkamp, Mari Carmen Romero-Mulero, Andreas Narr, Luisa Ladel, Lucie Hustin, Katharina Schönberger, Simon Renders, Sandro Altamura, Petra Zeisberger, Karin Jäcklein, Daniel Klimmeck, Alejo Rodriguez-Fraticelli, Fernando D Camargo, Leïla Perié, Andreas Trumpp, Nina Cabezas-Wallscheid2

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

用于同时读取单细胞谱系历史和基因表达谱的工程化 CRISPR-Cas9 小鼠系

Sarah Bowling, Duluxan Sritharan, Fernando G Osorio, Maximilian Nguyen, Priscilla Cheung, Alejo Rodriguez-Fraticelli, Sachin Patel, Wei-Chien Yuan, Yuko Fujiwara, Bin E Li, Stuart H Orkin, Sahand Hormoz, Fernando D Camargo

Cell Plasticity-Related Phenotypes and Taxanes Resistance in Castration-Resistant Prostate Cancer

去势抵抗性前列腺癌中的细胞可塑性相关表型和紫杉烷类药物耐药性

Natalia Jiménez, Òscar Reig, Ruth Montalbo, Maria Milà-Guasch, Lluis Nadal-Dieste, Giancarlo Castellano, Juan José Lozano, Iván Victoria, Albert Font, Alejo Rodriguez-Vida, Joan Carles, Cristina Suárez, Montserrat Domènech, Núria Sala-González, Pedro Luis Fernández, Leonardo Rodríguez-Carunchio, She