Ceramide-Induced Metabolic Stress Depletes Fumarate and Drives Mitophagy to Mediate Tumor Suppression.
神经酰胺诱导的代谢应激会消耗富马酸并驱动线粒体自噬,从而介导肿瘤抑制
期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-24-4042
Oleinik Natalia V, Atilgan Firdevs Cansu, Kassir Mohamed Faisal, Lee Han Gyul, Janneh Alhaji H, Wofford Wyatt, Walton Chase, Szulc Zdzislaw M, Hill Elizabeth G, Alekseyenko Alexander V, Cimen Huseyin, Hartman Jessica H, Voelkel-Johnson Christina, Lilly Michael B, Lemasters John J, Frizzell Norma, Yu Xue-Zhong, Mehrotra Shikhar, Ogretmen Besim