日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Current approaches and advances in placental toxicology

胎盘毒理学的最新研究方法和进展

Veiga-Lopez, Almudena; Elkin, Elana R; Harris, Sean M; Blake, Bevin E; Paquette, Alison G; Aleksunes, Lauren M; Stapleton, Phoebe A

Hierarchical Mechanistic Modeling of Complex Toxicity Endpoints from Public Concentration-Response Data

基于公共浓度-反应数据的复杂毒性终点分层机制建模

Chung, Elena; Russo, Daniel P; Aleksunes, Lauren M; Warner, Genoa R; Zhu, Hao

Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction-associated steatohepatitis in mice

小鼠饮食诱导的代谢功能障碍相关性脂肪性肝炎中,PXR磷酸化基序Ser347位点的突变会破坏脂质和胆汁酸稳态。

Basaly, Veronia; Henry, Zakiyah R; Taylor, Rulaiha E; Kong, Bo; Yang, Ill; Brinker, Anita; Yang, Zhenning; Zhou, Peihong; Joseph, Laurie B; Aleksunes, Lauren; Buckley, Brian; Negishi, Masahiko; Guo, Grace L

vToxiNet: a biologically constrained deep learning framework for interpretable prediction of drug-induced hepatotoxicity

vToxiNet:一种基于生物学约束的深度学习框架,用于对药物引起的肝毒性进行可解释的预测

Jia, Xuelian; Wang, Tong; Russo, Daniel P; Aleksunes, Lauren M; Xiao, Shuo; Zhu, Hao

Transporter-Mediated Uptake of Microcystin-LR in Human Trophoblasts: Regulation By Oxygen Concentration and Cell Fusion.

转运蛋白介导的微囊藻毒素-LR在人类滋养层细胞中的吸收:氧浓度和细胞融合的调节。

Campbell Michael Jeffrey, Patel Mokshitkumar, Jiang Chenghui, Wen Xia, Xiao Shuo, Aleksunes Lauren M

Developmental toxicity: artificial intelligence-powered assessments

发育毒性:人工智能驱动的评估

Wang, Tong; Jia, Xuelian; Aleksunes, Lauren M; Shen, Hui; Deng, Hong-Wen; Zhu, Hao

Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model

人源化免疫系统小鼠模型中免疫疗法诱导肾毒性的病理学发现

Asby, Sarah C; Thompson, Lauren E; Goedken, Michael; Lucia, Scott M; Dominguez, Adrian T; Kar, Adwitiya; Pitts, Todd M; Kiseljak-Vassiliades, Katja; Lang, Julie; Aleksunes, Lauren M; Joy, Melanie S

Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes

妊娠期真菌雌激素暴露:ABCG2 Q141K 变异对分娩和胎盘结局的影响

Rivera-Núñez, Zorimar; Kinkade, Carolyn; Brinker, Anita; Zhang, Ranran; Buckley, Brian; Brunner, Jessica; Ohman-Strickland, Pamela; Qiu, Xing; Qasem, Rani J; Fallon, John K; Smith, Philip C; Miller, Richard K; Salafia, Carolyn S; O'Connor, Thomas G; Aleksunes, Lauren M; Barrett, Emily S

Sociodemographic and dietary predictors of maternal and placental mycoestrogen concentrations in a US pregnancy cohort.

美国妊娠队列中母体和胎盘真菌雌激素浓度的社会人口学和饮食预测因素

Kinkade Carolyn W, Brinker Anita, Buckley Brian, Waysack Olivia, Fernandez I Diana, Kautz Amber, Meng Ying, Shi Huishan, Brunner Jessica, Ohman-Strickland Pamela, Groth Susan W, O'Connor Thomas G, Aleksunes Lauren M, Barrett Emily S, Rivera-Núñez Zorimar

Deletion of hepatic FXR leads to more severe MASH development in female mice

肝脏FXR基因缺失会导致雌性小鼠发生更严重的MASH(黏膜相关血液系统疾病)

Henry, Zakiyah R; Armstrong, Laura; Maliha, Syeda; Jia, Xuelian; Gao, Sophie; Taylor, Rulaiha E; Basaly, Veronia; Otersen, Katherine; Yang, Zhenning; Rizzolo, Daniel; Stofan, Mary; Meadows, Vik; Bhattacharya, Anisha; Zhou, Peihong; Yang, Ill; Brinker, Anita; Zhou, Lanjing; Zhu, Hao; Joseph, Laurie B; Buckley, Brian; Anthony, Tracy; Aleksunes, Lauren; Kong, Bo; Guo, Grace L