Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223
6-(2-氟-4-硝基苯基)-2-氧杂-6-氮杂螺[3.3]庚烷的实用且可规模化的两步法合成:强效抗生素候选药物TBI-223的关键中间体
期刊:Organic Process Research & Development
影响因子:3.5
doi:10.1021/acs.oprd.3c00148
Cardoso, Flavio S P; Kadam, Appasaheb L; Nelson, Ryan C; Tomlin, John W; Dahal, Dipendra; Kuehner, Christopher S; Gudvangen, Gard; Arduengo, Anthony J 3rd; Burns, Justina M; Aleshire, Sarah L; Snead, David R; Qu, Fengrui; Belmore, Ken; Ahmad, Saeed; Agrawal, Toolika; Sieber, Joshua D; Donsbach, Kai Oliver