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Atherosclerosis Plaque Reduction by Lycopene Is Mediated by Increased Energy Expenditure through AMPK and PPARα in ApoE KO Mice Fed with a High Fat Diet

在食用高脂饮食的 ApoE KO 小鼠中，番茄红素通过增加 AMPK 和 PPARα 的能量消耗来减少动脉粥样硬化斑块

doi:10.3390/biom12070973

Federica Mannino, Giovanni Pallio, Domenica Altavilla, Francesco Squadrito, Giovanna Vermiglio, Alessandra Bitto, Natasha Irrera

A Phase 1/2 Study of Flavocoxid, an Oral NF-κB Inhibitor, in Duchenne Muscular Dystrophy

口服 NF-κB 抑制剂 Flavocoxid 治疗杜氏肌营养不良症的 1/2 期研究

期刊:Brain Sciences

影响因子:2.7

doi:10.3390/brainsci11010115

Gian Luca Vita, Maria Sframeli, Norma Licata, Alessandra Bitto, Sara Romeo, Francesca Frisone, Annamaria Ciranni, Giovanni Pallio, Federica Mannino, M'Hammed Aguennouz, Carmelo Rodolico, Francesco Squadrito, Antonio Toscano, Sonia Messina, Giuseppe Vita

Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells

β-石竹烯通过诱导多发性骨髓瘤细胞凋亡和调节细胞周期发挥抗增殖作用

期刊:Cancers

影响因子:

doi:10.3390/cancers13225741

Federica Mannino, Giovanni Pallio, Roberta Corsaro, Letteria Minutoli, Domenica Altavilla, Giovanna Vermiglio, Alessandro Allegra, Ali H Eid, Alessandra Bitto, Francesco Squadrito, Natasha Irrera

Targeting Adenosine Receptor by Polydeoxyribonucleotide: An Effective Therapeutic Strategy to Induce White-to-Brown Adipose Differentiation and to Curb Obesity

聚脱氧核糖核苷酸靶向腺苷受体：诱导白色至棕色脂肪分化和抑制肥胖的有效治疗策略

期刊:Pharmaceuticals

影响因子:

doi:10.3390/ph14080728

Federica Mannino, Giovanni Pallio, Alessandra Bitto, Domenica Altavilla, Letteria Minutoli, Violetta Squadrito, Vincenzo Arcoraci, Domenico Antonio Giorgi, Igor Pirrotta, Francesco Squadrito, Natasha Irrera

信号转导

发表日期：2021

文献求助收藏

PDRN, a Bioactive Natural Compound, Ameliorates Imiquimod-Induced Psoriasis through NF-κB Pathway Inhibition and Wnt/β-Catenin Signaling Modulation

PDRN 是一种具有生物活性的天然化合物，可通过抑制 NF-κB 通路和调节 Wnt/β-Catenin 信号改善咪喹莫特诱发的银屑病

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms21041215

Natasha Irrera, Alessandra Bitto, Mario Vaccaro, Federica Mannino, Violetta Squadrito, Giovanni Pallio, Vincenzo Arcoraci, Letteria Minutoli, Antonio Ieni, Maria Lentini, Domenica Altavilla, Francesco Squadrito

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells

非共价免疫蛋白酶体抑制剂诱导多发性骨髓瘤 MM.1R 细胞的细胞周期停滞

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry

影响因子:5.6

doi:10.1080/14756366.2019.1594802

Roberta Ettari, Giovanni Pallio, Gabriele Pizzino, Natasha Irrera, Maria Zappalà, Santina Maiorana, Carla Di Chio, Domenica Altavilla, Francesco Squadrito, Alessandra Bitto

β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors

β-石竹烯通过 CB2 和 PPAR-γ 受体之间的相互作用缓解小鼠胶原抗体诱发的关节炎 (CAIA)

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom9080326

Natasha Irrera, Angela D'Ascola, Giovanni Pallio, Alessandra Bitto, Emanuela Mazzon, Federica Mannino, Violetta Squadrito, Vincenzo Arcoraci, Letteria Minutoli, Giuseppe Maurizio Campo, Angela Avenoso, Elisa Benedetta Bongiorno, Mario Vaccaro, Francesco Squadrito, Domenica Altavilla

PCB-126 effects on aryl hydrocarbon receptor, ubiquitin and p53 expression levels in a fish product (Sparus aurata L.)

PCB-126 对鱼产品（Sparus aurata L.）中芳烃受体、泛素和 p53 表达水平的影响

期刊:Natural Product Research

影响因子:1.9

doi:10.1080/14786419.2017.1320794

Margherita Calò, Alessandra Bitto, Patrizia Lo Cascio, Filippo Giarratana, Domenica Altavilla, Teresa Gervasi, Luca Campone, Nicola Cicero, Patrizia Licata

信号转导

发表日期：2018

文献求助收藏

Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity

聚脱氧核糖核苷酸对小鼠镉中毒模型的神经保护作用

期刊:Oxidative Medicine and Cellular Longevity

影响因子:

doi:10.1155/2018/4285694

Herbert R Marini, Domenico Puzzolo, Antonio Micali, Elena Bianca Adamo, Natasha Irrera, Antonina Pisani, Giovanni Pallio, Vincenzo Trichilo, Consuelo Malta, Alessandra Bitto, Francesco Squadrito, Domenica Altavilla, Letteria Minutoli

神经

发表日期：2018

文献求助收藏

Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives

利用新型酰胺衍生物靶向免疫蛋白酶体来抑制神经炎症

Atherosclerosis Plaque Reduction by Lycopene Is Mediated by Increased Energy Expenditure through AMPK and PPARα in ApoE KO Mice Fed with a High Fat Diet

在食用高脂饮食的 ApoE KO 小鼠中，番茄红素通过增加 AMPK 和 PPARα 的能量消耗来减少动脉粥样硬化斑块

A Phase 1/2 Study of Flavocoxid, an Oral NF-κB Inhibitor, in Duchenne Muscular Dystrophy

口服 NF-κB 抑制剂 Flavocoxid 治疗杜氏肌营养不良症的 1/2 期研究

Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells

β-石竹烯通过诱导多发性骨髓瘤细胞凋亡和调节细胞周期发挥抗增殖作用

Targeting Adenosine Receptor by Polydeoxyribonucleotide: An Effective Therapeutic Strategy to Induce White-to-Brown Adipose Differentiation and to Curb Obesity

聚脱氧核糖核苷酸靶向腺苷受体：诱导白色至棕色脂肪分化和抑制肥胖的有效治疗策略

PDRN, a Bioactive Natural Compound, Ameliorates Imiquimod-Induced Psoriasis through NF-κB Pathway Inhibition and Wnt/β-Catenin Signaling Modulation

PDRN 是一种具有生物活性的天然化合物，可通过抑制 NF-κB 通路和调节 Wnt/β-Catenin 信号改善咪喹莫特诱发的银屑病

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells

非共价免疫蛋白酶体抑制剂诱导多发性骨髓瘤 MM.1R 细胞的细胞周期停滞

β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors

β-石竹烯通过 CB2 和 PPAR-γ 受体之间的相互作用缓解小鼠胶原抗体诱发的关节炎 (CAIA)

PCB-126 effects on aryl hydrocarbon receptor, ubiquitin and p53 expression levels in a fish product (Sparus aurata L.)

PCB-126 对鱼产品（Sparus aurata L.）中芳烃受体、泛素和 p53 表达水平的影响

Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity

聚脱氧核糖核苷酸对小鼠镉中毒模型的神经保护作用