日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections

宿主来源的氧化磷脂通过表观遗传机制沉默白细胞介素-10,从而促进对感染的致命性炎症反应。

Marco Di Gioia ,Valentina Poli ,Piao J Tan ,Roberto Spreafico ,Anne Chu ,Alex G Cuenca ,Zhongyang Wu ,Mehdi Benamar ,Laura Pandolfi ,Federica Meloni ,Fatemeh Askarian ,Jason Hsiao ,Elizaveata Borroum ,Victor Nizet ,Philip L S M Gordts ,Joseph L Witztum ,Talal A Chatila ,Janet Chou ,Xu Zhou ,James R Springstead ,Ivan Zanoni

Adjuvant conditioning shapes the adaptive immune response promoting immunotolerance via NLRP3/interleukin-1

佐剂预处理通过NLRP3/白细胞介素-1途径影响适应性免疫反应,促进免疫耐受。

Thais Boccia ,Weikang Pan ,Victor Fattori ,Rodrigo Cervantes-Diaz ,Michael S Rogers ,Ivan Zanoni ,Alex G Cuenca

Adjuvant conditioning induces an immunosuppressive milieu that delays alloislet rejection through the expansion of myeloid-derived suppressor cells

佐剂调节可诱导免疫抑制环境,通过扩增髓系抑制细胞来延缓异体胰岛排斥

Jifu Ge, Weikang Pan, Noel J Feeney, Leah Ott, Emily Anderson, Alessandro Alessandrini, Ivan Zanoni, James F Markmann, Alex G Cuenca

Intragraft B cell differentiation during the development of tolerance to kidney allografts is associated with a regulatory B cell signature revealed by single cell transcriptomics

在肾移植耐受性发展过程中,移植体内B细胞分化与单细胞转录组学揭示的调节性B细胞特征相关。

Michael Tyler Guinn ,Edward S Szuter ,Takahiro Yokose ,Jifu Ge ,Ivy A Rosales ,Kashish Chetal ,Ruslan I Sadreyev ,Alex G Cuenca ,Daniel Kreisel ,Peter T Sage ,Paul S Russell ,Joren C Madsen ,Robert B Colvin ,Alessandro Alessandrini

Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

宿主衍生的氧化磷脂启动效应器触发的免疫,在遇到微生物时促进杀伤力

Marco Di Gioia, Valentina Poli, Piao J Tan, Roberto Spreafico, Anne Chu, Alex G Cuenca, Philip Lsm Gordts, Laura Pandolfi, Federica Meloni, Joseph L Witztum, Janet Chou, James R Springstead, Ivan Zanoni

TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis

TRIF 依赖性先天免疫激活对于新生儿革兰氏阴性脓毒症的存活至关重要

Alex G Cuenca, Dallas N Joiner, Lori F Gentile, Angela L Cuenca, James L Wynn, Kindra M Kelly-Scumpia, Philip O Scumpia, Kevin E Behrns, Philip A Efron, Dina Nacionales, Chao Lui, Shannon M Wallet, Westley H Reeves, Clayton E Mathews, Lyle L Moldawer

Delayed emergency myelopoiesis following polymicrobial sepsis in neonates

新生儿多重微生物感染脓毒症后紧急骨髓造血延迟

Alex G Cuenca, Angela L Cuenca, Lori F Gentile, Philip A Efron, Saleem Islam, Lyle L Moldawer, David W Kays, Shawn D Larson

Protective immunity and defects in the neonatal and elderly immune response to sepsis

保护性免疫以及新生儿和老年人对脓毒症的免疫反应缺陷

Lori F Gentile, Dina C Nacionales, M Cecilia Lopez, Erin Vanzant, Angela Cuenca, Alex G Cuenca, Ricardo Ungaro, Ben E Szpila, Shawn Larson, Anna Joseph, Frederick A Moore, Christiaan Leeuwenburgh, Henry V Baker, Lyle L Moldawer, Philip A Efron

Aged mice are unable to mount an effective myeloid response to sepsis

老年小鼠无法对脓毒症产生有效的骨髓反应

Dina C Nacionales, Lori F Gentile, Erin Vanzant, M Cecilia Lopez, Angela Cuenca, Alex G Cuenca, Ricardo Ungaro, Yi Li, Tezcan Ozrazgat Baslanti, Azra Bihorac, Frederick A Moore, Henry V Baker, Christiaan Leeuwenburgh, Lyle L Moldawer, Philip A Efron

Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia

肿瘤诱导的髓系细胞扩增在癌症恶病质中的新作用

Cuenca, Alex G; Cuenca, Angela L; Winfield, Robert D; Joiner, Dallas N; Gentile, Lori; Delano, Matthew J; Kelly-Scumpia, Kindra M; Scumpia, Philip O; Matheny, Michael K; Scarpace, Philip J; Vila, Lizette; Efron, Philip A; LaFace, Drake M; Moldawer, Lyle L