Multiselective RAS(ON) inhibition targets oncogenic RAS and overcomes RAS-mediated resistance to FLT3i and BCL2i in AML
多选择性 RAS(ON) 抑制剂靶向致癌 RAS，并克服急性髓系白血病 (AML) 中 RAS 介导的对 FLT3 抑制剂和 BCL2 抑制剂的耐药性。
期刊:Blood
影响因子:23.1
doi:10.1182/blood.2025030558
Popescu, Bogdan; Jones, Matthew F; Piao, Madison; Tran, Elaine; Koh, Andrew; Lomeli, Isabelle; Peretz, Cheryl A C; Murad, Natalia; Abelson, Sydney; Morales, Carolina; Rivera, Jose M; Batingana, Alexa Rane; D'Souza, Jeevitha; Pikman, Yana; Cheng, Michael L; Logan, Aaron C; Huang, Benjamin J; Stieglitz, Elliot; Smith, Catherine C
