Alexander W S相关文献与解析，生知库 | 链接生命科学的每一步

The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

细胞因子信号抑制因子-1的SOCS盒对于体内细胞因子活性的抑制至关重要。

期刊:Proceedings of the National Academy of Sciences of the United States of America

Zhang, J G; Metcalf, D; Rakar, S; Asimakis, M; Greenhalgh, C J; Willson, T A; Starr, R; Nicholson, S E; Carter, W; Alexander, W S; Hilton, D J; Nicola, N A

SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice

SOCS1缺陷会导致乳腺发育加速，并能挽救催乳素受体缺陷小鼠的泌乳功能。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.880801

Lindeman, G J; Wittlin, S; Lada, H; Naylor, M J; Santamaria, M; Zhang, J G; Starr, R; Hilton, D J; Alexander, W S; Ormandy, C J; Visvader, J

Functional analysis of Asb-1 using genetic modification in mice.

利用基因改造小鼠对Asb-1进行功能分析

期刊:Molecular and Cellular Biology

影响因子:2.7

doi:10.1128/MCB.21.18.6189-6197.2001

Kile B T, Metcalf D, Mifsud S, DiRago L, Nicola N A, Hilton D J, Alexander W S

发表日期：2001

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The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene

在 IFN-γ 杂合子且缺乏 SOCS-1 基因的小鼠中，致命性心肌炎和多发性肌炎的发生发展

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.160255197

Metcalf, D; Di Rago, L; Mifsud, S; Hartley, L; Alexander, W S

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

细胞因子信号抑制因子中保守的SOCS盒基序可与延伸蛋白B和C结合，并可能将结合蛋白与蛋白酶体降解偶联。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.96.5.2071

Zhang, J G; Farley, A; Nicholson, S E; Willson, T A; Zugaro, L M; Simpson, R J; Moritz, R L; Cary, D; Richardson, R; Hausmann, G; Kile, B T; Kent, S B; Alexander, W S; Metcalf, D; Hilton, D J; Nicola, N A; Baca, M

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

SOCS蛋白的突变分析表明，抑制LIF和IL-6信号转导需要双结构域，但抑制机制不同。

期刊:EMBO Journal

影响因子:8.3

doi:10.1093/emboj/18.2.375

Nicholson, S E; Willson, T A; Farley, A; Starr, R; Zhang, J G; Baca, M; Alexander, W S; Metcalf, D; Hilton, D J; Nicola, N A

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

缺乏细胞因子信号抑制因子-1的小鼠出现肝脏退化和淋巴细胞缺陷

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.95.24.14395

Starr, R; Metcalf, D; Elefanty, A G; Brysha, M; Willson, T A; Nicola, N A; Hilton, D J; Alexander, W S

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells

瘦素可以诱导造血细胞的增殖、分化和功能激活。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.93.25.14564

Gainsford, T; Willson, T A; Metcalf, D; Handman, E; McFarlane, C; Ng, A; Nicola, N A; Alexander, W S; Hilton, D J

细胞生物学

发表日期：1996

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Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl

淋巴细胞转化中的癌基因协同作用：体外 E mu-myc 转基因前 B 细胞的恶性转化受 vH-ras 或 v-raf 增强，但不受 v-abl 增强。

期刊:Molecular and Cellular Biology

影响因子:2.7

doi:10.1128/mcb.9.1.67-73.1989

Alexander, W S; Adams, J M; Cory, S

Primary meningococcal conjunctivitis: an unusual case of transmission by saliva

原发性脑膜炎球菌性结膜炎：一例罕见的唾液传播病例

The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

细胞因子信号抑制因子-1的SOCS盒对于体内细胞因子活性的抑制至关重要。

SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice

SOCS1缺陷会导致乳腺发育加速，并能挽救催乳素受体缺陷小鼠的泌乳功能。

Functional analysis of Asb-1 using genetic modification in mice.

利用基因改造小鼠对Asb-1进行功能分析

The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene

在 IFN-γ 杂合子且缺乏 SOCS-1 基因的小鼠中，致命性心肌炎和多发性肌炎的发生发展

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

细胞因子信号抑制因子中保守的SOCS盒基序可与延伸蛋白B和C结合，并可能将结合蛋白与蛋白酶体降解偶联。

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

SOCS蛋白的突变分析表明，抑制LIF和IL-6信号转导需要双结构域，但抑制机制不同。

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

缺乏细胞因子信号抑制因子-1的小鼠出现肝脏退化和淋巴细胞缺陷

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells

瘦素可以诱导造血细胞的增殖、分化和功能激活。

Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl

淋巴细胞转化中的癌基因协同作用：体外 E mu-myc 转基因前 B 细胞的恶性转化受 vH-ras 或 v-raf 增强，但不受 v-abl 增强。