日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1

Epstein-Barr 病毒裂解开关蛋白 ZEBRA/Zta/BZLF1 的 DNA 甲基化依赖性位点选择性的结构基础

Florent Bernaudat, Montse Gustems, Johannes Günther, Mizar F Oliva, Alexander Buschle, Christine Göbel, Priscilla Pagniez, Julien Lupo, Luca Signor, Christoph W Müller, Patrice Morand, Michael Sattler, Wolfgang Hammerschmidt, Carlo Petosa

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

在裂解再激活的第一阶段,Epstein-Barr 病毒会使转录组失活,并破坏宿主细胞的染色质结构

Alexander Buschle, Paulina Mrozek-Gorska, Filippo M Cernilogar, Andreas Ettinger, Dagmar Pich, Stefan Krebs, Bianca Mocanu, Helmut Blum, Gunnar Schotta, Tobias Straub, Wolfgang Hammerschmidt

Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones

人类 ORC/MCM 的活性基因密度较低,与复制时间相关,但并不界定起始区

Nina Kirstein, Alexander Buschle, Xia Wu, Stefan Krebs, Helmut Blum, Elisabeth Kremmer, Ina M Vorberg, Wolfgang Hammerschmidt, Laurent Lacroix, Olivier Hyrien, Benjamin Audit, Aloys Schepers

Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection

利用CRISPR-Cas9介导的高效基因敲除技术在原代人B细胞中用于Epstein-Barr病毒感染的功能遗传学研究

Ezgi Akidil ,Manuel Albanese ,Alexander Buschle ,Adrian Ruhle ,Dagmar Pich ,Oliver T Keppler ,Wolfgang Hammerschmidt

BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV

BZLF1 与染色质重塑因子相互作用,促进 EBV 潜伏感染的逃脱

Marisa Schaeffner, Paulina Mrozek-Gorska, Alexander Buschle, Anne Woellmer, Takanobu Tagawa, Filippo M Cernilogar, Gunnar Schotta, Nils Krietenstein, Corinna Lieleg, Philipp Korber, Wolfgang Hammerschmidt