Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders
1,5-二取代 α-氨基四唑衍生物的设计、合成和生物学评价，作为非共价炎症小体-caspase-1 复合物抑制剂，具有治疗免疫和炎症疾病的潜在应用价值
期刊:European Journal of Medicinal Chemistry
影响因子:6
doi:10.1016/j.ejmech.2021.114002
Fausta Ulgheri, Pietro Spanu, Francesco Deligia, Giovanni Loriga, Maria Pia Fuggetta, Iris de Haan, Ajay Chandgudge, Matthew Groves, Alexander Domling
