日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere

肌联蛋白激酶泛素化使自噬受体与肌节中的机械信号对齐

Julius Bogomolovas, Jennifer R Fleming, Barbara Franke, Bruno Manso, Bernd Simon, Alexander Gasch, Marija Markovic, Thomas Brunner, Ralph Knöll, Ju Chen, Siegfried Labeit, Martin Scheffner, Christine Peter, Olga Mayans

Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition

亮氨酸的抗骨骼肌萎缩作用涉及肌生长抑制素抑制

André Cruz, Andrea Ferian, Paula K N Alves, William Jose Silva, Mirella Ribeiro Bento, Alexander Gasch, Siegfried Labeit, Anselmo Sigari Moriscot

Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

肌联蛋白/MURF1信号复合物的扰动与鱼类模型和人类患者的肥厚性心肌病有关

Yuta Higashikuse, Nishant Mittal, Takuro Arimura, Sung Han Yoon, Mayumi Oda, Hirokazu Enomoto, Ruri Kaneda, Fumiyuki Hattori, Takeshi Suzuki, Atsushi Kawakami, Alexander Gasch, Tetsushi Furukawa, Siegfried Labeit, Keiichi Fukuda, Akinori Kimura, Shinji Makino

Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia

小分子抑制 MuRF1 可减轻心脏恶病质中的骨骼肌萎缩和功能障碍

Thomas Scott Bowen, Volker Adams, Sarah Werner, Tina Fischer, Paulien Vinke, Maria Noel Brogger, Norman Mangner, Axel Linke, Peter Sehr, Joe Lewis, Dittmar Labeit, Alexander Gasch, Siegfried Labeit

Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors

自噬、SQSTM1、SH3GLB1 和 TRIM63 在烟碱乙酰胆碱受体周转中的作用

Muzamil Majid Khan, Siegfried Strack, Franziska Wild, Akira Hanashima, Alexander Gasch, Kathrin Brohm, Markus Reischl, Silvia Carnio, Dittmar Labeit, Marco Sandri, Siegfried Labeit, Rüdiger Rudolf

Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line

肌联蛋白激酶是一种无活性的假激酶支架,支持 MuRF1 募集至肌节 M 线

Julijus Bogomolovas, Alexander Gasch, Felix Simkovic, Daniel J Rigden, Siegfried Labeit, Olga Mayans

Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathways

MuRF1 调节烟碱乙酰胆碱受体周转,将肌肉活动与内/溶酶体和萎缩途径联系起来

Rüdiger Rudolf, Julius Bogomolovas, Siegfried Strack, Kyeong-Rok Choi, Muzamil Majid Khan, Anika Wagner, Kathrin Brohm, Akira Hanashima, Alexander Gasch, Dittmar Labeit, Siegfried Labeit