PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN
PRMT5 抑制调节 E2F1 甲基化和基因调控网络，从而对 JAK2V617F 突变型 MPN 产生治疗效果
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-20-0026
Friederike Pastore, Neha Bhagwat, Alessandro Pastore, Aliaksandra Radzisheuskaya, Abdul Karzai, Aishwarya Krishnan, Bing Li, Robert L Bowman, Wenbin Xiao, Aaron D Viny, Anouar Zouak, Young C Park, Keith B Cordner, Stephanie Braunstein, Jesper L Maag, Alexander Grego, Jaanvi Mehta, Min Wang, Hong Lin
