日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma

SAGA 复合物的 KAT 模块维持 MYCN 扩增神经母细胞瘤中的致癌基因表达程序

Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier

Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors

CDK8 抑制的转录拮抗作用可提高 MEK 抑制剂的治疗效果

Clare F Malone #, Minjee Kim #, Gabriela Alexe, Kathleen Engel, Alexandra B Forman, Amanda Robichaud, Amy Saur Conway, Amy Goodale, Ashleigh Meyer, Delan Khalid, Allen Thayakumar, John M Hatcher, Nathanael S Gray, Federica Piccioni, Kimberly Stegmaier

Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer

选择性调节泛必需蛋白作为癌症治疗策略

Clare F Malone, Neekesh V Dharia, Guillaume Kugener, Alexandra B Forman, Michael V Rothberg, Mai Abdusamad, Alfredo Gonzalez, Miljan Kuljanin, Amanda L Robichaud, Amy Saur Conway, Joshua M Dempster, Brenton R Paolella, Nancy Dumont, Volker Hovestadt, Joseph D Mancias, Scott T Younger, David E Root,