日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation

Arp2/3 失活导致椎间盘和软骨退化,并伴有 TonEBP 介导的渗透适应失调

Steven Tessier, Alexandra C Doolittle, Kimheak Sao, Jeremy D Rotty, James E Bear, Veronica Ulici, Richard F Loeser, Irving M Shapiro, Brian O Diekman, Makarand V Risbud

COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells

高渗条件下钙-TonEBP信号轴介导的COX-2表达在髓核细胞中发挥渗透保护作用

Hyowon Choi, Weera Chaiyamongkol, Alexandra C Doolittle, Zariel I Johnson, Shilpa S Gogate, Zachary R Schoepflin, Irving M Shapiro, Makarand V Risbud

TNF-α promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells

TNF-α 促进转录因子 TonEBP/NFAT5 的核富集,从而选择性地控制髓核细胞中的炎症但不控制渗透调节反应

Zariel I Johnson, Alexandra C Doolittle, Joseph W Snuggs, Irving M Shapiro, Christine L Le Maitre, Makarand V Risbud