日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Repeated sensitization of mice with microfilariae of Litomosoides sigmodontis induces pulmonary eosinophilia in an IL-33-dependent manner

用 Litomosoides sigmodontis 微丝蚴反复致敏小鼠以 IL-33 依赖的方式诱发肺嗜酸性粒细胞增多症

Benjamin Lenz, Alexandra Ehrens, Jesuthas Ajendra, Frederic Risch, Joséphine Gal, Anna-Lena Neumann, Julia J Reichwald, Wiebke Strutz, Henry J McSorley, Coralie Martin, Achim Hoerauf, Marc P Hübner

Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

微丝蚴以 Dectin-1 依赖的方式触发嗜酸性粒细胞胞外 DNA 陷阱

Alexandra Ehrens, Benjamin Lenz, Anna-Lena Neumann, Samuela Giarrizzo, Julia Jennifer Reichwald, Stefan Julian Frohberger, Wiebke Stamminger, Benedikt Christian Buerfent, Frédéric Fercoq, Coralie Martin, Daniel Kulke, Achim Hoerauf, Marc Peter Hübner

Eosinophils and Neutrophils Eliminate Migrating Strongyloides ratti Larvae at the Site of Infection in the Context of Extracellular DNA Trap Formation

嗜酸性粒细胞和中性粒细胞在细胞外 DNA 陷阱形成的情况下消灭感染部位迁移的鼠类圆线虫幼虫

Alexandra Ehrens, Nikolas Rüdiger, Lennart Heepmann, Lara Linnemann, Wiebke Hartmann, Marc P Hübner, Minka Breloer

S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis

S100A8/S100A9 缺乏会增加中性粒细胞活化和对丝虫 Litomosoides sigmodontis 入侵感染性 L3 幼虫的保护性免疫反应

Stefan J Frohberger, Frederic Fercoq, Anna-Lena Neumann, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Indulekha Karunakaran, Estelle Remion, Thomas Vogl, Achim Hoerauf, Coralie Martin, Marc P Hübner

Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro

奥芬达唑在体内介导对丝虫线虫 Litomosoides sigmodontis 的杀大丝虫作用,并在体外抑制盘尾丝虫的活力

Marc P Hübner, Coralie Martin, Sabine Specht, Marianne Koschel, Bettina Dubben, Stefan J Frohberger, Alexandra Ehrens, Martina Fendler, Dominique Struever, Edward Mitre, Nathaly Vallarino-Lhermitte, Suzanne Gokool, Sara Lustigman, Manfred Schneider, Simon Townson, Achim Hoerauf, Ivan Scandale

Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils

与 IL-4R、IL-5 或嗜酸性粒细胞单一敲除的动物相比,缺乏 IL-4R/IL-5 的动物对 L. sigmodontis 感染的敏感性最高

Stefan J Frohberger, Jesuthas Ajendra, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Benedikt C Buerfent, Katrin Gentil, Achim Hoerauf, Marc P Hübner