日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of Antituberculars with Favorable Potency and Pharmacokinetics through Structure-Based and Ligand-Based Modeling

通过基于结构和基于配体的建模方法筛选具有良好效力和药代动力学特性的抗结核药物

Warapande, Vedang; Meng, Fanwang; Bozan, Alexandra; Graff, David E; Fromer, Jenna C; Mughal, Khadija; Mohideen, Faheem K; Shivangi; Paruchuri, Sindhuja; Johnston, Melanie L; Sharma, Pankaj; Crea, Timothy R; Rudraraju, Reshma S; George, Amir; Folvar, Camilla; Nelson, Andrew M; Neiditch, Matthew B; Zimmerman, Matthew D; Coley, Connor W; Freundlich, Joel S

The sodium-bicarbonate cotransporter Slc4a5 mediates feedback at the first synapse of vision

碳酸氢钠共转运体 Slc4a5 介导视觉第一个突触的反馈

Rei Morikawa, Tiago M Rodrigues, Helene Marianne Schreyer, Cameron S Cowan, Sarah Nadeau, Alexandra Graff-Meyer, Claudia P Patino-Alvarez, Mohammad Hossein Khani, Josephine Jüttner, Botond Roska

Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex

锥体神经元形成活跃的、瞬时的、多层回路,这些回路在新皮层形成初期会受到自闭症相关突变的干扰。

Martin Munz ,Arjun Bharioke ,Georg Kosche ,Verónica Moreno-Juan ,Alexandra Brignall ,Tiago M Rodrigues ,Alexandra Graff-Meyer ,Talia Ulmer ,Stephanie Haeuselmann ,Dinko Pavlinic ,Nicole Ledergerber ,Brigitte Gross-Scherf ,Balázs Rózsa ,Jacek Krol ,Simone Picelli ,Cameron S Cowan ,Botond Roska

HP1 proteins regulate nucleolar structure and function by secluding pericentromeric constitutive heterochromatin

HP1 蛋白通过隔离着丝粒周围组成异染色质来调节核仁结构和功能

Daniel Ballmer, Mathieu Tardat, Raphael Ortiz, Alexandra Graff-Meyer, Evgeniy A Ozonov, Christel Genoud, Antoine Hfm Peters, Grigorios Fanourgakis

Complete loss of H3K9 methylation dissolves mouse heterochromatin organization

H3K9 甲基化的完全丧失溶解了小鼠异染色质的组织

Thomas Montavon, Nicholas Shukeir, Galina Erikson, Bettina Engist, Megumi Onishi-Seebacher, Devon Ryan, Yaarub Musa, Gerhard Mittler, Alexandra Graff Meyer, Christel Genoud, Thomas Jenuwein

Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule - single vesicle level by fluorescence correlation spectroscopy and single particle imaging

通过荧光相关光谱和单粒子成像对细胞外囊泡分选域进行系统表征,并在单分子-单囊泡水平上进行量化

Giulia Corso, Wolf Heusermann, Dominic Trojer, André Görgens, Emmanuelle Steib, Johannes Voshol, Alexandra Graff, Christel Genoud, Yi Lee, Justin Hean, Joel Z Nordin, Oscar P B Wiklander, Samir El Andaloussi, Nicole Meisner-Kober

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

DuoMab:一种基于 CrossMab 的新型 IgG 衍生抗体形式,可增强抗体依赖性细胞介导的细胞毒性

Claudio Sustmann, Steffen Dickopf, Jörg T Regula, Hubert Kettenberger, Michael Mølhøj, Christian Gassner, Diana Weininger, Sebastian Fenn, Tobias Manigold, Lothar Kling, Klaus-Peter Künkele, Manfred Schwaiger, Birgit Bossenmaier, Julia J Griese, Karl-Peter Hopfner, Alexandra Graff-Meyer, Henning Sta

TMEM41B is a novel regulator of autophagy and lipid mobilization

TMEM41B 是一种新型的自噬和脂质动员调节剂

Francesca Moretti, Phil Bergman, Stacie Dodgson, David Marcellin, Isabelle Claerr, Jonathan M Goodwin, Rowena DeJesus, Zhao Kang, Christophe Antczak, Damien Begue, Debora Bonenfant, Alexandra Graff, Christel Genoud, John S Reece-Hoyes, Carsten Russ, Zinger Yang, Gregory R Hoffman, Matthias Mueller, 

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles

淀粉样脑小体是致密的膜状迷路,含有结构保存完好的细胞器

Paula P Navarro, Christel Genoud, Daniel Castaño-Díez, Alexandra Graff-Meyer, Amanda J Lewis, Yvonne de Gier, Matthias E Lauer, Markus Britschgi, Bernd Bohrmann, Stephan Frank, Jürgen Hench, Gabriel Schweighauser, Annemieke J M Rozemuller, Wilma D J van de Berg, Henning Stahlberg, Sarah H Shahmoradi

Fast Homogeneous En Bloc Staining of Large Tissue Samples for Volume Electron Microscopy

用于体积电子显微镜的大组织样本的快速均匀整体染色

Christel Genoud, Benjamin Titze, Alexandra Graff-Meyer, Rainer W Friedrich