日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dose-Related Mutagenic and Clastogenic Effects of Benzo[ b]fluoranthene in Mouse Somatic Tissues Detected by Duplex Sequencing and the Micronucleus Assay

通过双重测序和微核试验检测苯并[b]荧蒽在小鼠体细胞组织中的剂量相关致突变和致染色体断裂作用

David M Schuster, Danielle P M LeBlanc, Gu Zhou, Matthew J Meier, Annette E Dodge, Paul A White, Alexandra S Long, Andrew Williams, Cheryl Hobbs, Alex Diesing, Stephanie L Smith-Roe, Jesse J Salk, Francesco Marchetti, Carole L Yauk

Application of a new approach methodology (NAM)-based strategy for genotoxicity assessment of data-poor compounds

应用基于新方法论 (NAM) 的策略对数据贫乏的化合物进行遗传毒性评估

Anne-Marie V Fortin, Alexandra S Long, Andrew Williams, Matthew J Meier, Julie Cox, Claire Pinsonnault, Carole L Yauk, Paul A White

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (TiparpH532A) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality

2,3,7,8-四氯二苯并二恶英 (TCDD) 诱导的聚 ADP 核糖聚合酶 (TIPARP/PARP7) 催化突变小鼠 (TiparpH532A) 对 TCDD 诱导的肝毒性和致死性的敏感性增加

David Hutin, Alexandra S Long, Kim Sugamori, Peng Shao, Sachin Kumar Singh, Marit Rasmussen, Ninni Elise Olafsen, Solveig Pettersen, Giulia Grimaldi, Denis M Grant, Jason Matthews

In vitro mutagenicity of selected environmental carcinogens and their metabolites in MutaMouse FE1 lung epithelial cells

选定的环境致癌物及其代谢物在 MutaMouse FE1 肺上皮细胞中的体外致突变性

Lisa Hölzl-Armstrong, Andrea Nævisdal, Julie A Cox, Alexandra S Long, Nikolai L Chepelev, David H Phillips, Paul A White, Volker M Arlt

Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene

通过对多个遗传毒性终点进行基准剂量分析,可以对 MutaMouse 对口服苯并[a]芘的反应进行稳健的跨组织比较

Alexandra S Long, John W Wills, Dorothy Krolak, Matthew Guo, Stephen D Dertinger, Volker M Arlt, Paul A White

Oral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations

口服市售的以煤焦油为基础的路面封层会导致小鼠基因损伤和突变

Alexandra S Long, Margaret Watson, Volker M Arlt, Paul A White