日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor AKTIP

层蛋白和核形态的联合改变影响肿瘤相关因子 AKTIP 的定位

Mattia La Torre #, Chiara Merigliano #, Klizia Maccaroni, Alexandre Chojnowski, Wah Ing Goh, Maria Giubettini, Fiammetta Vernì, Cristina Capanni, Daniela Rhodes, Graham Wright, Brian Burke, Silvia Soddu, Romina Burla, Isabella Saggio

Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy

通过 AAV 介导的基因转导破坏 LINC 复合物可防止 Lamin 诱发的心肌病进展

Ruth Jinfen Chai #, Hendrikje Werner #, Peter Yiqing Li, Yin Loon Lee, Khaing Thet Nyein, Irina Solovei, Tuan Danh Anh Luu, Bhavya Sharma, Raju Navasankari, Martina Maric, Lois Yu En Sim, Ying Jie Loh, Edita Aliwarga, Jason Wen Long Cheong, Alexandre Chojnowski, Matias Ilmari Autio, Yu Haiyang, Kenn

AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody

AKTIP 与 ESCRT I 相互作用,是 ESCRT III 亚基向中体募集所必需的

Chiara Merigliano, Romina Burla, Mattia La Torre, Simona Del Giudice, Hsiangling Teo, Chong Wai Liew, Alexandre Chojnowski, Wah Ing Goh, Yolanda Olmos, Klizia Maccaroni, Maria Giubettini, Irene Chiolo, Jeremy G Carlton, Domenico Raimondo, Fiammetta Vernì, Colin L Stewart, Daniela Rhodes, Graham D Wr

Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria

异染色质丢失是哈钦森-吉尔福德早衰症中早衰蛋白诱导的 DNA 损伤的决定因素

Alexandre Chojnowski, Peh Fern Ong, Mattheus Xing Rong Foo, David Liebl, Louis-Peter Hor, Colin L Stewart, Oliver Dreesen

Loss of lamin B1 is a biomarker to quantify cellular senescence in photoaged skin

层蛋白 B1 的缺失是量化光老化皮肤细胞衰老的生物标志物

Audrey Shimei Wang, Peh Fern Ong, Alexandre Chojnowski, Carlos Clavel, Oliver Dreesen

Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria

Progerin 可降低哈钦森-吉尔福德早衰症中的 LAP2α-端粒关联

Alexandre Chojnowski, Peh Fern Ong, Esther S M Wong, John S Y Lim, Rafidah A Mutalif, Raju Navasankari, Bamaprasad Dutta, Henry Yang, Yi Y Liow, Siu K Sze, Thomas Boudier, Graham D Wright, Alan Colman, Brian Burke, Colin L Stewart, Oliver Dreesen

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence

层蛋白 B1 波动对细胞增殖和衰老有不同的影响

Oliver Dreesen, Alexandre Chojnowski, Peh Fern Ong, Tian Yun Zhao, John E Common, Declan Lunny, E Birgitte Lane, Shu Jin Lee, Leah A Vardy, Colin L Stewart, Alan Colman