日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity

与左心发育不全综合征有关的线粒体 MICOS 复合基因维持心脏收缩力和肌动球蛋白完整性

Katja Birker #, Shuchao Ge #, Natalie J Kirkland #, Jeanne L Theis #, James Marchant, Zachary C Fogarty, Maria A Missinato, Sreehari Kalvakuri, Paul Grossfeld, Adam J Engler, Karen Ocorr, Timothy J Nelson, Alexandre R Colas, Timothy M Olson, Georg Vogler, Rolf Bodmer

Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm

心房颤动的多平台建模确定受磷蛋白是心律的中枢调节器

Anaïs Kervadec, James Kezos, Haibo Ni, Michael Yu, James Marchant, Sean Spiering, Suraj Kannan, Chulan Kwon, Peter Andersen, Rolf Bodmer, Eleonora Grandi, Karen Ocorr, Alexandre R Colas

Genetic architecture of natural variation of cardiac performance from flies to humans

从苍蝇到人类心脏功能自然变异的遗传结构

Saswati Saha #, Lionel Spinelli #, Jaime A Castro Mondragon, Anaïs Kervadec, Michaela Lynott, Laurent Kremmer, Laurence Roder, Sallouha Krifa, Magali Torres, Christine Brun, Georg Vogler, Rolf Bodmer, Alexandre R Colas, Karen Ocorr, Laurent Perrin

Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling

新生多肽相关复合物和信号识别颗粒在心脏发育和重塑中具有心脏特异性作用

Analyne M Schroeder, Tanja Nielsen, Michaela Lynott, Georg Vogler, Alexandre R Colas, Rolf Bodmer

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

PGC1/PPAR 通过 YAP1 和 SF3B2 在单细胞水平上驱动心肌细胞成熟

Sean A Murphy, Matthew Miyamoto, Anaïs Kervadec, Suraj Kannan, Emmanouil Tampakakis, Sandeep Kambhampati, Brian Leei Lin, Sam Paek, Peter Andersen, Dong-Ik Lee, Renjun Zhu, Steven S An, David A Kass, Hideki Uosaki, Alexandre R Colas, Chulan Kwon

Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness

小分子探针揭示了将应激信号与 TCF/LEF 和 Wnt 反应联系起来的激酶级联

Jiongjia Cheng, Masanao Tsuda, Karl Okolotowicz, Mary Dwyer, Paul J Bushway, Alexandre R Colas, Joseph J Lancman, Dennis Schade, Isaac Perea-Gil, Arne A N Bruyneel, Jaechol Lee, Nirmal Vadgama, Justine Quach, Wesley L McKeithan, Travis L Biechele, Joseph C Wu, Randall T Moon, P Duc Si Dong, Ioannis

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome

患者特异性基因组学和跨物种功能分析表明,LRP2与左心发育不良综合征有关。

Jeanne L Theis # ,Georg Vogler # ,Maria A Missinato # ,Xing Li ,Tanja Nielsen ,Xin-Xin I Zeng ,Almudena Martinez-Fernandez ,Stanley M Walls ,Anaïs Kervadec ,James N Kezos ,Katja Birker ,Jared M Evans ,Megan M O'Byrne ,Zachary C Fogarty ,André Terzic ,Paul Grossfeld ,Karen Ocorr ,Timothy J Nelson # ,Timothy M Olson # ,Alexandre R Colas # ,Rolf Bodmer #

Silencing of CCR4-NOT complex subunits affects heart structure and function

CCR4-NOT 复合物亚基的沉默影响心脏结构和功能

Lisa Elmén, Claudia B Volpato, Anaïs Kervadec, Santiago Pineda, Sreehari Kalvakuri, Nakissa N Alayari, Luisa Foco, Peter P Pramstaller, Karen Ocorr, Alessandra Rossini, Anthony Cammarato, Alexandre R Colas, Andrew A Hicks, Rolf Bodmer

Dietary Emulsifier Sodium Stearoyl Lactylate Alters Gut Microbiota in vitro and Inhibits Bacterial Butyrate Producers

膳食乳化剂硬脂酰乳酸钠可体外改变肠道微生物群并抑制细菌丁酸盐产生菌

Lisa Elmén, Jaime E Zlamal, David A Scott, Ryan B Lee, Daniel J Chen, Alexandre R Colas, Dmitry A Rodionov, Scott N Peterson

Model system identification of novel congenital heart disease gene candidates: focus on RPL13

新型先天性心脏病候选基因的模型系统识别:重点关注RPL13

Analyne M Schroeder, Massoud Allahyari, Georg Vogler, Maria A Missinato, Tanja Nielsen, Michael S Yu, Jeanne L Theis, Lars A Larsen, Preeya Goyal, Jill A Rosenfeld, Timothy J Nelson, Timothy M Olson, Alexandre R Colas, Paul Grossfeld, Rolf Bodmer