日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function

IL-2可通过趋化因子受体发出信号,促进调节性T细胞的抑制功能。

Hao Sun ,Ho-Sup Lee ,Sarah Hyun-Ji Kim ,Mikhael Fernandes de Lima ,Alexandre R Gingras ,Qinyi Du ,Wilma McLaughlin ,Jailail Ablack ,Miguel A Lopez-Ramirez ,Frederic Lagarrigue ,Zhichao Fan ,John T Chang ,Derek VanDyke ,Jamie B Spangler ,Mark H Ginsberg

Phostensin enables lymphocyte integrin activation and population of peripheral lymphoid organs

磷酸化蛋白能够激活淋巴细胞整合素并促进外周淋巴器官的增殖

Ho-Sup Lee #, Hao Sun #, Frédéric Lagarrigue #, Sarah Hyun Ji Kim, Jay W Fox, Nicholas E Sherman, Alexandre R Gingras, Mark H Ginsberg

Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4+ T Cells

Rap1 与 Talin1 和 MRL 蛋白直接结合促进 CD4+ T 细胞中的整合素活化

Frederic Lagarrigue, Boyang Tan, Qinyi Du, Zhichao Fan, Miguel A Lopez-Ramirez, Alexandre R Gingras, Hsin Wang, Weiwei Qi, Hao Sun

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling

Kindlin-3 募集至质膜,先于高亲和力 β2 整合素和中性粒细胞停止滚动

Lai Wen, Alex Marki, Payel Roy, Sara McArdle, Hao Sun, Zhichao Fan, Alexandre R Gingras, Mark H Ginsberg, Klaus Ley

Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells

抑制 HEG1-KRIT1 相互作用可增加内皮细胞中的 KLF4 和 KLF2 表达

Miguel Alejandro Lopez-Ramirez, Sara McCurdy, Wenqing Li, Mark K Haynes, Preston Hale, Karol Francisco, Killian Oukoloff, Matthew Bautista, Chelsea H J Choi, Hao Sun, Brendan Gongol, John Y Shyy, Carlo Ballatore, Larry A Sklar, Alexandre R Gingras

Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling

前沿科学:跨膜结构域的柔性扭结会损害 β2 整合素的延伸和细胞停滞

Hao Sun, Zhichao Fan, Alexandre R Gingras, Miguel A Lopez-Ramirez, Mark H Ginsberg, Klaus Ley

Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem

Rap1 结合和 talin F1 结构域中的脂质依赖性螺旋串联促进整合素活化

Alexandre R Gingras #, Frederic Lagarrigue #, Monica N Cuevas, Andrew J Valadez, Marcus Zorovich, Wilma McLaughlin, Miguel Alejandro Lopez-Ramirez, Nicolas Seban, Klaus Ley, William B Kiosses, Mark H Ginsberg

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation

Rap1 与 talin 1 F0 结构域结合对小鼠血小板 GPIIb-IIIa 活化的贡献很小

Frederic Lagarrigue, Alexandre R Gingras, David S Paul, Andrew J Valadez, Monica N Cuevas, Hao Sun, Miguel A Lopez-Ramirez, Benjamin T Goult, Sanford J Shattil, Wolfgang Bergmeier, Mark H Ginsberg

Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

整合素β7跨膜结构域拓扑的传递促进肠道淋巴组织发育

Hao Sun, Frederic Lagarrigue, Alexandre R Gingras, Zhichao Fan, Klaus Ley, Mark H Ginsberg

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity

玻璃心将 Rasip1 锚定在内皮细胞-细胞连接处以维持血管完整性

Bart-Jan de Kreuk, Alexandre R Gingras, James Dr Knight, Jian J Liu, Anne-Claude Gingras, Mark H Ginsberg