Blockade of Tau hyperphosphorylation and Aβ₁₋₄₂ generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and σ₁ receptor agonist, in a nontransgenic mouse model of Alzheimer's disease
在阿尔茨海默病非转基因小鼠模型中,氨基四氢呋喃衍生物 ANAVEX2-73(一种混合毒蕈碱和 σ₁ 受体激动剂)可阻断 Tau 过度磷酸化和 Aβ₁₋₄₂ 生成
期刊:Neuropsychopharmacology
影响因子:6.6
doi:10.1038/npp.2013.70
Valentine Lahmy, Johann Meunier, Susanna Malmström, Gaelle Naert, Laurent Givalois, Seung Hyun Kim, Vanessa Villard, Alexandre Vamvakides, Tangui Maurice