A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain
激酶组的功能筛选确定 Polo 样激酶 4 是恶性横纹肌样瘤以及可能的其他脑胚胎肿瘤的潜在治疗靶点
期刊:Pediatric Blood & Cancer
影响因子:2.4
doi:10.1002/pbc.26551
Simone Treiger Sredni, Mario Suzuki, Jian-Ping Yang, Jacek Topczewski, Anders W Bailey, Tufan Gokirmak, Jeffrey N Gross, Alexandre de Andrade, Akihide Kondo, David R Piper, Tadanori Tomita