日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress

DR5二硫键作为蛋白质折叠应激的传感器和效应器发挥作用

Mary E Law # ,Zaafir M Dulloo # ,Samantha R Eggleston ,Gregory P Takacs ,Grace M Alexandrow ,Young Il Lee ,Mengxiong Wang ,Brian Hardy ,Hanyu Su ,Bianca Forsyth ,Parag Das ,Pran K Datta ,Chi-Wu Chiang ,Abhisheak Sharma ,Siva Rama Raju Kanumuri ,Olga A Guryanova ,Jeffrey K Harrison ,Boaz Tirosh ,Ronald K Castellano ,Brian K Law

Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function

鉴定可破坏CMG复制体功能的ATP竞争性人CMG解旋酶抑制剂,用于癌症干预

Shengyan Xiang ,Kendall C Craig ,Xingju Luo ,Darcy L Welch ,Renan B Ferreira ,Harshani R Lawrence ,Nicholas J Lawrence ,Damon R Reed ,Mark G Alexandrow

The CMG helicase and cancer: a tumor "engine" and weakness with missing mutations

CMG解旋酶与癌症:肿瘤“引擎”与缺失突变导致的弱点

Xiang, Shengyan; Reed, Damon R; Alexandrow, Mark G

Modeling phenotypic heterogeneity towards evolutionarily inspired osteosarcoma therapy

为进化启发的骨肉瘤治疗建立表型异质性模型

Darcy L Welch, Brooke L Fridley, Ling Cen, Jamie K Teer, Sean J Yoder, Fredrik Pettersson, Liping Xu, Chia-Ho Cheng, Yonghong Zhang, Mark G Alexandrow, Shengyan Xiang, Mark Robertson-Tessi, Joel S Brown, Jonathan Metts, Andrew S Brohl, Damon R Reed

Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function

鉴定用于癌症干预的选择性 ATP 竞争性 CMG 解旋酶抑制剂,以破坏 CMG 复制体功能

Shengyan Xiang, Xingju Luo, Darcy Welch, Damon R Reed, Mark G Alexandrow

An evolutionary framework for treating pediatric sarcomas

儿童肉瘤治疗的演进框架

Reed, Damon R; Metts, Jonathan; Pressley, Mariyah; Fridley, Brooke L; Hayashi, Masanori; Isakoff, Michael S; Loeb, David M; Makanji, Rikesh; Roberts, Ryan D; Trucco, Matteo; Wagner, Lars M; Alexandrow, Mark G; Gatenby, Robert A; Brown, Joel S

Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer: Myc Over-Activation of CMG Helicases Drives Tumorigenesis and Creates a Vulnerability in CMGs for Therapeutic Intervention

Myc 和复制型 CMG 解旋酶:癌症的产生与毁灭:Myc 过度激活 CMG 解旋酶驱动肿瘤发生,并使 CMG 成为治疗干预的脆弱靶点

Reed, Damon R; Alexandrow, Mark G

Myc-driven chromatin accessibility regulates Cdc45 assembly into CMG helicases

Myc 驱动的染色质可及性调节 Cdc45 组装成 CMG 解旋酶

Brook S Nepon-Sixt #, Victoria L Bryant #, Mark G Alexandrow

TGFβ1 Cell Cycle Arrest Is Mediated by Inhibition of MCM Assembly in Rb-Deficient Conditions

TGFβ1 细胞周期停滞是通过抑制 Rb 缺乏条件下的 MCM 组装来介导的

Brook S Nepon-Sixt, Mark G Alexandrow

DNase I Chromatin Accessibility Analysis

DNase I 染色质可及性分析

Brook S Nepon-Sixt, Mark G Alexandrow