日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An evolved AAV variant enables efficient genetic engineering of murine T cells

一种改良的AAV变体能够有效地对小鼠T细胞进行基因工程改造。

William A Nyberg,Jonathan Ark,Angela To,Sylvanie Clouden,Gabriella Reeder,Joseph J Muldoon,Jing-Yi Chung,William H Xie,Vincent Allain,Zachary Steinhart,Christopher Chang,Alexis Talbot,Sandy Kim,Alan Rosales,L Patrick Havlik,Harold Pimentel,Aravind Asokan,Justin Eyquem

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

使用混合 ssDNA 修复模板和小分子混合物在原代细胞中进行高产基因组工程

Brian R Shy #, Vivasvan S Vykunta #, Alvin Ha, Alexis Talbot, Theodore L Roth, David N Nguyen, Wolfgang G Pfeifer, Yan Yi Chen, Franziska Blaeschke, Eric Shifrut, Shane Vedova, Murad R Mamedov, Jing-Yi Jing Chung, Hong Li, Ruby Yu, David Wu, Jeffrey Wolf, Thomas G Martin, Carlos E Castro, Lumeng Ye,

BCLXL PROTAC degrader DT2216 targets secondary plasma cell leukemia addicted to BCLXL for survival

BCLXL PROTAC 降解剂 DT2216 靶向依赖 BCLXL 生存的继发性浆细胞白血病

Ophélie Champion, Alana Soler, Sophie Maïga, Céline Bellanger, Catherine Pellat-Deceunynck, Alexis Talbot, Cyrille Touzeau, Martine Amiot, Patricia Gomez-Bougie

NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia

NUDT21通过B细胞急性淋巴细胞白血病中的mRNA选择性多聚腺苷酸化来限制CD19水平

Matthew T Witkowski # ,Soobeom Lee # ,Eric Wang # ,Anna K Lee ,Alexis Talbot ,Chao Ma ,Nikolaos Tsopoulidis ,Justin Brumbaugh ,Yaqi Zhao ,Kathryn G Roberts ,Simon J Hogg ,Sofia Nomikou ,Yohana E Ghebrechristos ,Palaniraja Thandapani ,Charles G Mullighan ,Konrad Hochedlinger ,Weiqiang Chen ,Omar Abdel-Wahab ,Justin Eyquem ,Iannis Aifantis

Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies

CAR-T 细胞的联合筛选确定了下一代免疫疗法所需的多种免疫信号域

Daniel B Goodman, Camillia S Azimi, Kendall Kearns, Alexis Talbot, Kiavash Garakani, Julie Garcia, Nisarg Patel, Byungjin Hwang, David Lee, Emily Park, Vivasvan S Vykunta, Brian R Shy, Chun Jimmie Ye, Justin Eyquem, Alexander Marson, Jeffrey A Bluestone, Kole T Roybal8

The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance

多发性骨髓瘤细胞的表面组学研究提示了潜在的免疫治疗策略和耐药蛋白标志物。

Ian D Ferguson ,Bonell Patiño-Escobar ,Sami T Tuomivaara ,Yu-Hsiu T Lin ,Matthew A Nix ,Kevin K Leung ,Corynn Kasap ,Emilio Ramos ,Wilson Nieves Vasquez ,Alexis Talbot ,Martina Hale ,Akul Naik ,Audrey Kishishita ,Priya Choudhry ,Antonia Lopez-Girona ,Weili Miao ,Sandy W Wong ,Jeffrey L Wolf ,Thomas G Martin 3rd ,Nina Shah ,Scott Vandenberg ,Sonam Prakash ,Lenka Besse ,Christoph Driessen ,Avery D Posey Jr ,R Dyche Mullins ,Justin Eyquem ,James A Wells ,Arun P Wiita

The long non-coding RNA CRNDE regulates growth of multiple myeloma cells via an effect on IL6 signalling

长链非编码 RNA CRNDE 通过影响 IL6 信号传导来调节多发性骨髓瘤细胞的生长

Antoine David, Simone Zocchi, Alexis Talbot, Caroline Choisy, Ashley Ohnona, Julien Lion, Wendy Cuccuini, Jean Soulier, Bertrand Arnulf, Jean-Christophe Bories, Michele Goodhardt, David Garrick