日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Host Aging Induces a Senescent-Like Phenotype in Neutrophils and Altered Transcriptional Responses to Streptococcus pneumoniae

宿主衰老诱导中性粒细胞出现衰老样表型并改变对肺炎链球菌的转录反应

Battaglia, Michael C; Bhalla, Manmeet; Marzullo, Brandon; Betadpur, Anagha; Lenhard, Alexsandra P; Mohamed, Rania Hassan; Kalem, Murat C; Heinzinger, Lauren R; Leus, Pathricia A; Labarron, Samuel; Garrett-Sinha, Lee Ann; Mecsas, Joan; Blumental-Perry, Anna; Bou Ghanem, Elsa N

Adenosine 2B Receptor Signaling Impairs Vaccine-Mediated Protection Against Pneumococcal Infection in Young Hosts by Blunting Neutrophil Killing of Antibody-Opsonized Bacteria

腺苷2B受体信号传导通过减弱中性粒细胞对抗体调理细菌的杀伤作用,损害疫苗介导的对幼龄宿主肺炎球菌感染的保护作用

Simmons, Shaunna R; Lenhard, Alexsandra P; Battaglia, Michael C; Bou Ghanem, Elsa N

Adenosine 2B receptor signaling impairs vaccine-mediated protection against pneumococcal infection in young hosts by blunting neutrophil killing of antibody opsonized bacteria

腺苷2B受体信号传导会削弱疫苗介导的对幼龄宿主肺炎球菌感染的保护作用,其机制是通过抑制中性粒细胞对抗体调理细菌的杀伤作用。

Simmons, Shaunna R; Lenhard, Alexsandra P; Battaglia, Michael C; Bou Ghanem, Elsa N

Host aging induces a senescent-like phenotype in neutrophils and altered transcriptional responses to Streptococcus pneumoniae

宿主衰老会诱导中性粒细胞出现衰老样表型,并改变其对肺炎链球菌的转录反应。

Battaglia, Michael C; Bhalla, Manmeet; Marzullo, Brandon; Betadpur, Anagha; Lenhard, Alexsandra P; Mohamed, Rania Hassan; Kalem, Murat C; Heinzinger, Lauren R; Leus, Pathricia A; Garrett-Sinha, Lee Ann; Mecsas, Joan; Blumental-Perry, Anna; Ghanem, Elsa N Bou

Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection

激活 A1 腺苷受体信号可促进老年小鼠在肺炎链球菌感染后早期肺中性粒细胞募集

Shaunna R Simmons, Sydney E Herring, Essi Y I Tchalla, Alexsandra P Lenhard, Manmeet Bhalla, Elsa N Bou Ghanem