日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PPP1R2 stimulates protein phosphatase-1 through stabilisation of dynamic subunit interactions

PPP1R2 通过稳定动态亚基相互作用来刺激蛋白磷酸酶-1 的活性。

Lemaire, Sarah; Ferreira, Mónica; Claes, Zander; Derua, Rita; Lake, Madryn; Van der Hoeven, Gerd; Withof, Fabienne; Cao, Xinyu; Greiner, Elora C; Kettenbach, Arminja N; Van Eynde, Aleyde; Bollen, Mathieu

SDS22 coordinates the assembly of holoenzymes from nascent protein phosphatase-1

SDS22协调新生蛋白磷酸酶-1组装成全酶。

Cao, Xinyu; Lake, Madryn; Van der Hoeven, Gerd; Claes, Zander; Del Pino García, Javier; Lemaire, Sarah; Greiner, Elora C; Karamanou, Spyridoula; Van Eynde, Aleyde; Kettenbach, Arminja N; Natera de Benito, Daniel; Carrera García, Laura; Hernando Davalillo, Cristina; Ortez, Carlos; Nascimento, Andrés; Urreizti, Roser; Bollen, Mathieu

Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases

利用自主裂解细菌系统进行细胞内蛋白质药物输送可减少肿瘤生长和转移

Vishnu Raman #, Nele Van Dessel #, Christopher L Hall, Victoria E Wetherby, Samantha A Whitney, Emily L Kolewe, Shoshana M K Bloom, Abhinav Sharma, Jeanne A Hardy, Mathieu Bollen, Aleyde Van Eynde, Neil S Forbes

Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1

磷酸酶调节因子NIPP1缺失可增强DNA修复能力并提高对化学诱导致癌作用的抵抗力。

Verbinnen, Iris; Boens, Shannah; Ferreira, Monica; Szekér, Kathelijne; Van Wijk, Louise; Van Eynde, Aleyde; Bollen, Mathieu

Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation

磷酸酶调节剂NIPP1抑制趋化因子驱动的皮肤炎症

Iris Verbinnen, Marloes Jonkhout, Kifayathullah Liakath-Ali, Kathelijne Szekér, Mónica Ferreira, Shannah Boens, Raphael Rouget, Margareta Nikolic, Susan Schlenner, Aleyde Van Eynde, Mathieu Bollen

Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics

蛋白磷酸酶1的功能和治疗潜力:来自小鼠遗传学的启示

Ferreira, Mónica; Beullens, Monique; Bollen, Mathieu; Van Eynde, Aleyde

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells

更正:MELK-T1 是一种小分子蛋白激酶 MELK 抑制剂,可降低增殖癌细胞的 DNA 损伤耐受性。

Beke, Lijs; Kig, Cenk; Linders, Joannes T M; Boens, Shannah; Boeckx, An; van Heerde, Erika; Parade, Marc; De Bondt, An; Van den Wyngaert, Ilse; Bashir, Tarig; Ogata, Souichi; Meerpoel, Lieven; Van Eynde, Aleyde; Johnson, Christopher N; Beullens, Monique; Brehmer, Dirk; Bollen, Mathieu

The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2

睾丸中蛋白磷酸酶 1 调节剂 NIPP1 的缺失导致组蛋白甲基转移酶 EZH2 的过度磷酸化和降解

Mónica Ferreira, Iris Verbinnen, Margarida Fardilha, Aleyde Van Eynde, Mathieu Bollen

A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions

利用低活性亚基融合的蛋白磷酸酶PP1全酶的底物捕获策略

Dan Wu, Veerle De Wever, Rita Derua, Claudia Winkler, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen

Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks

PP1-NIPP1 的过度表达限制了细胞修复 DNA 双链断裂的能力

Claudia Winkler, Raphael Rouget, Dan Wu, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen