日期:
2020 年 — 2026 年
2020
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2026
影响因子:

Don't Be Surprised When These Surprise You: Some Infrequently Studied Sphingoid Bases, Metabolites, and Factors That Should Be Kept in Mind During Sphingolipidomic Studies

以下这些内容可能会让你感到惊讶:一些研究较少的鞘氨醇碱、代谢物以及在鞘脂组学研究中应注意的因素

Alfred H Merrill Jr

The regulation of p53, p38 MAPK, JNK and XBP-1s by sphingosine kinases in human embryonic kidney cells

鞘氨醇激酶对人胚胎肾细胞中 p53、p38 MAPK、JNK 和 XBP-1s 的调控

Mariam Alsanafi, Samuel L Kelly, Melissa McNaughton, Alfred H Merrill Jr, Nigel J Pyne, Susan Pyne

Native and Polyubiquitinated Forms of Dihydroceramide Desaturase Are Differentially Linked to Human Embryonic Kidney Cell Survival

二氢神经酰胺去饱和酶的天然形式和多泛素化形式与人类胚胎肾细胞存活存在差异

Mariam Alsanafi, Samuel L Kelly, Karawan Jubair, Melissa McNaughton, Rothwelle J Tate, Alfred H Merrill Jr, Susan Pyne, Nigel J Pyne

Novel Interconnections in Lipid Metabolism Revealed by Overexpression of Sphingomyelin Synthase-1

鞘磷脂合酶-1的过度表达揭示了脂质代谢中的新相互联系

Gergana M Deevska, Patrick P Dotson 2nd, Alexander A Karakashian, Giorgis Isaac, Mark Wrona, Samuel B Kelly, Alfred H Merrill Jr, Mariana N Nikolova-Karakashian

Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis

通过改变神经酰胺酰基链长引起的氧化应激降低了网格蛋白介导的内吞作用的速率

Giora Volpert, Shifra Ben-Dor, Ohad Tarcic, Jingjing Duan, Ann Saada, Alfred H Merrill Jr, Yael Pewzner-Jung, Anthony H Futerman

Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons

鞘氨醇 1-磷酸 (S1P) 裂解酶缺乏会通过循环增加鞘脂的形成,而以牺牲神经元中的从头生物合成为代价

Nadine Hagen-Euteneuer, Dieter Lütjohann, Hyejung Park, Alfred H Merrill Jr, Gerhild van Echten-Deckert

Modulation of ceramide synthase activity via dimerization

通过二聚化调节神经酰胺合酶活性

Elad L Laviad, Samuel Kelly, Alfred H Merrill Jr, Anthony H Futerman

Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction

小鼠 CD4+ T 细胞膜和免疫突触的鞘脂组成随年龄变化,表明葡萄糖神经酰胺与年龄相关的 T 细胞功能障碍有关

Alberto Molano, Zhaofeng Huang, Melissa G Marko, Angelo Azzi, Dayong Wu, Elaine Wang, Samuel L Kelly, Alfred H Merrill Jr, Stephen C Bunnell, Simin Nikbin Meydani

Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

Safingol(L-苏型鞘氨醇)通过抑制 PKC 和 PI3-激酶通路诱导实体肿瘤细胞自噬

Jesse Coward, Grazia Ambrosini, Elgilda Musi, Jean-Philip Truman, Adriana Haimovitz-Friedman, Jeremy C Allegood, Elaine Wang, Alfred H Merrill Jr, Gary K Schwartz

Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals

伏马毒素 B1 抑制神经酰胺合酶导致 1-脱氧鞘氨醇积累:由哺乳动物细胞系和动物生物合成的一类新型生物活性 1-脱氧鞘氨醇碱基和 1-脱氧二氢神经酰胺

Nicholas C Zitomer, Trevor Mitchell, Kenneth A Voss, Genevieve S Bondy, Sarah T Pruett, Ethel C Garnier-Amblard, Lanny S Liebeskind, Hyejung Park, Elaine Wang, M Cameron Sullards, Alfred H Merrill Jr, Ronald T Riley