日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

RNA Sequencing of Sepsis Patients Informs Tests to Quickly Diagnose Pathogens and Resistance

对脓毒症患者进行RNA测序,有助于快速诊断病原体和耐药性。

Monaghan, Sean F; Shin, Jaewook; Armstead, Brandon E; Ayala, Alfred; Cohen, Maya; Fairbrother, William G; Levy, Mitchell M; Lillard, Kwesi K; Raggi, Emanuele; Nau, Gerard J; Fredericks, Alger M

Predicting nonsense-mediated mRNA decay from splicing events in sepsis using RNA-sequencing data

利用RNA测序数据预测脓毒症中剪接事件导致的无义介导的mRNA降解

Shin, Jaewook; Fredericks, Alger M; Armstead, Brandon E; Ayala, Alfred; Cohen, Maya; Fairbrother, William G; Levy, Mitchell M; Lillard, Kwesi K; Raggi, Emanuele; Nau, Gerard J; Monaghan, Sean F

Predicting Nonsense-mediated mRNA Decay from Splicing Events in Sepsis using RNA-Sequencing Data

利用RNA测序数据预测脓毒症中剪接事件导致的无义介导的mRNA降解

Shin, Jaewook; Fredericks, Alger M; Armstead, Brandon E; Ayala, Alfred; Cohen, Maya; Fairbrother, William G; Levy, Mitchell M; Lillard, Kwesi K; Raggi, Emanuele; Nau, Gerard J; Monaghan, Sean F

The unusual gene architecture of polyubiquitin is created by dual-specific splice sites

多泛素的不寻常基因结构是由双特异性剪接位点产生的

Chaorui Duan, Truman Mooney, Luke Buerer, Cory Bowers, Stephen Rong, Seong Won Kim, Alger M Fredericks, Sean F Monaghan, William G Fairbrother

Application of single cell multiomics points to changes in chromatin accessibility near calcitonin receptor like receptor and a possible role for adrenomedullin in the post-shock lung

单细胞多组学分析表明,降钙素受体样受体附近的染色质可及性发生改变,肾上腺髓质素可能在休克后肺损伤中发挥作用。

Armstead, Brandon E; Lee, Chung Sunny; Chen, Yaping; Zhao, Runping; Chung, Chun-Shiang; Fredericks, Alger M; Monaghan, Sean F; Ayala, Alfred

Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice

Prg4基因敲除小鼠关节内注射rhPRG4后四足步态及胫股关节凋亡因子的调控

Yang, Daniel S; Dickerson, Edward E; Zhang, Ling X; Richendrfer, Holly; Karamchedu, Padmini N; Badger, Gary J; Schmidt, Tannin A; Fredericks, Alger M; Elsaid, Khaled A; Jay, Gregory D

Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations

通过深度 RNA 测序和分子动力学模拟鉴定 COVID-19 患者非 ACE2 阻断中和抗体并阐明其机制

Alger M Fredericks, Kyle W East, Yuanjun Shi, Jinchan Liu, Federica Maschietto, Alfred Ayala, William G Cioffi, Maya Cohen, William G Fairbrother, Craig T Lefort, Gerard J Nau, Mitchell M Levy, Jimin Wang, Victor S Batista, George P Lisi, Sean F Monaghan

Deep RNA sequencing of intensive care unit patients with COVID-19

重症监护室 COVID-19 患者的深度 RNA 测序

Alger M Fredericks, Maximilian S Jentzsch, William G Cioffi, Maya Cohen, William G Fairbrother, Shivam J Gandhi, Elizabeth O Harrington, Gerard J Nau, Jonathan S Reichner, Corey E Ventetuolo, Mitchell M Levy, Alfred Ayala, Sean F Monaghan

Future directions for high-throughput splicing assays in precision medicine

精准医学中高通量剪接检测的未来发展方向

Rhine, Christy L; Neil, Christopher; Glidden, David T; Cygan, Kamil J; Fredericks, Alger M; Wang, Jing; Walton, Nephi A; Fairbrother, William G

The effects of structure on pre-mRNA processing and stability

结构对前体mRNA加工和稳定性的影响

Soemedi, Rachel; Cygan, Kamil J; Rhine, Christy L; Glidden, David T; Taggart, Allison J; Lin, Chien-Ling; Fredericks, Alger M; Fairbrother, William G