日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development and preclinical testing of a naloxone prodrug depot for extended protection against opioid overdose

纳洛酮前药缓释剂的研发及临床前试验,旨在延长对阿片类药物过量的保护作用

Aldawod, Hala; Patel, Arjun D; Emara, Rasha; Liang, Dengpan; Ho, Joshua S; Amin, Toufiq Ul; Tuhin, Md Tariqul Haque; Balgoname, Abdulmalek; Kiani, Avishan; Ajlouny, Jumana M; Felmlee, Melanie A; Park, Miki S; Jasti, Bhaskara R; Chan, William K; Uchizono, James A; Alhamadsheh, Mamoun M

Effects of 17β-Estradiol Treatment on Metabolic Function and Aortic Relaxation in Castrated Male Rats.

17β-雌二醇治疗对去势雄性大鼠代谢功能和主动脉舒张的影响。

Islam Rifat Ara, Razan Md Rahatullah, Poojari Ankita, Rahman Mohammad Moshiur, Wei Hao, Alhamadsheh Hana S, Felmlee Melanie, Rabiee Atefeh, Esfandiarei Mitra, Rahimian Roshanak

Enhancing the Pharmacokinetic Profile of Interleukin 2 through Site-Specific Conjugation to a Selective Small-Molecule Transthyretin Ligand

通过与选择性小分子转甲状腺素配体进行位点特异性结合来增强白细胞介素 2 的药代动力学特性

Fang Liu, Toufiq Ul Amin, Dengpan Liang, Miki S Park, Mamoun M Alhamadsheh

Hydrophilic Small Molecules That Harness Transthyretin To Enhance the Safety and Efficacy of Targeted Chemotherapeutic Agents

利用转甲状腺素蛋白增强靶向化疗药物安全性和有效性的亲水性小分子

Arindom Pal, Wabel Albusairi, Fang Liu, Md Tariqul Haque Tuhin, Mark Miller, Dengpan Liang, Hyun Joo, Toufiq Ul Amin, Elizabeth A Wilson, Jesika S Faridi, Miki Park, Mamoun M Alhamadsheh

Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis

AG10 对转甲状腺素蛋白的焓驱动稳定化模拟了一种自然发生的遗传变异,可预防转甲状腺素蛋白淀粉样变性

Mark Miller, Arindom Pal, Wabel Albusairi, Hyun Joo, Beverly Pappas, Md Tariqul Haque Tuhin, Dengpan Liang, Raghavendra Jampala, Fang Liu, Jared Khan, Marjon Faaij, Miki Park, William Chan, Isabella Graef, Robert Zamboni, Neil Kumar, Jonathan Fox, Uma Sinha, Mamoun Alhamadsheh

A biomimetic approach for enhancing the in vivo half-life of peptides

增强肽体内半衰期的仿生方法

Sravan C Penchala, Mark R Miller, Arindom Pal, Jin Dong, Nikhil R Madadi, Jinghang Xie, Hyun Joo, Jerry Tsai, Patrick Batoon, Vyacheslav Samoshin, Andreas Franz, Trever Cox, Jesse Miles, William K Chan, Miki S Park, Mamoun M Alhamadsheh

Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity

有效的动力学稳定剂可防止转甲状腺素蛋白介导的心肌细胞蛋白毒性

Mamoun M Alhamadsheh, Stephen Connelly, Ahryon Cho, Natàlia Reixach, Evan T Powers, Dorothy W Pan, Ian A Wilson, Jeffery W Kelly, Isabella A Graef

Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine.

由 S-腺苷-L-蛋氨酸生物合成盐孢酰胺 A 聚酮合酶底物氯乙基丙二酰辅酶 A

Eustáquio Alessandra S, McGlinchey Ryan P, Liu Yuan, Hazzard Christopher, Beer Laura L, Florova Galina, Alhamadsheh Mamoun M, Lechner Anna, Kale Andrew J, Kobayashi Yoshihisa, Reynolds Kevin A, Moore Bradley S

Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates

利用烷基辅酶A二硫键抑制剂和酰基辅酶A底物探测结核分枝杆菌FabH二聚体两个亚基的反应性和底物特异性

Sachdeva, Sarbjot; Musayev, Faik; Alhamadsheh, Mamoun M; Neel Scarsdale, J; Tonie Wright, H; Reynolds, Kevin A