日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of HSPE1 as a new actionable cancer vulnerability leads to an innovative and effective combination therapy for pancreatic ductal adenocarcinoma

将 HSPE1 鉴定为一种新的可靶向癌症脆弱性基因,可促成一种针对胰腺导管腺癌的创新且有效的联合疗法。

Boudreault, Julien; Rahimirad, Shima; Wang, Ni; Yan, Gang; Lima, Leslie Chaltel; Poulet, Sophie; Dai, Meiou; Ali, Suhad; Lebrun, Jean-Jacques

A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathways as a differentiation therapeutic target in breast cancer.

催乳素与致癌 YAP-CCN2 通路之间一种新的具有临床意义的拮抗作用,可作为乳腺癌分化治疗靶点

Liu Xueqing, Moamer Alaa, Gomes da Silva Roger, Shoham-Amizlev Aidan, Hamam Dana, Shams Anwar, Lebrun Jean-Jacques, Ali Suhad

Author Correction: Targeting the DYRK1A kinase prevents cancer progression and metastasis and promotes cancer cells response to G1/S targeting chemotherapy drugs

作者更正:靶向 DYRK1A 激酶可阻止癌症进展和转移,并促进癌细胞对 G1/S 期靶向化疗药物的反应。

Laham, Amina Jamal; El-Awady, Raafat; Saber-Ayad, Maha; Wang, Ni; Yan, Gang; Boudreault, Julien; Ali, Suhad; Lebrun, Jean-Jacques

Combined in vitro/in vivo genome-wide CRISPR screens in triple negative breast cancer identify cancer stemness regulators in paclitaxel resistance

结合体外/体内全基因组 CRISPR 筛选技术,在三阴性乳腺癌中鉴定出与紫杉醇耐药性相关的癌症干细胞调控因子。

Yan, Gang; Dai, Meiou; Poulet, Sophie; Wang, Ni; Boudreault, Julien; Daliah, Girija; Ali, Suhad; Lebrun, Jean-Jacques

Correction: Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation

更正:Smad信号通路拮抗STAT5介导的基因转录和乳腺上皮细胞分化。

Cocolakis, Eftihia; Dai, Meiou; Drevet, Loren; Ho, Joanne; Haines, Eric; Ali, Suhad; Lebrun, Jean-Jacques

Study protocol for the sheMATTERS study (iMproving cArdiovascular healTh in new moThERS): a randomized behavioral trial assessing the effect of a self-efficacy enhancing breastfeeding intervention on postpartum blood pressure and breastfeeding continuation in women with hypertensive disorders of pregnancy

sheMATTERS 研究(改善新妈妈心血管健康)的研究方案:一项随机行为试验,旨在评估增强自我效能的母乳喂养干预措施对妊娠期高血压疾病女性产后血压和母乳喂养持续性的影响。

Dayan, Natalie; Smith, Graeme; Nedelchev, Atanas; Abenhaim, Haim; Brown, Richard; Da Costa, Deborah; Ali, Suhad; Perlman, Jesseca; Nguyen, Tuong-Vi; Dennis, Cindy-Lee; Abdelmageed, Wael; Semenic, Sonia

Terminal differentiation and anti-tumorigenic effects of prolactin in breast cancer

催乳素在乳腺癌中的终末分化和抗肿瘤作用

Ali, Suhad; Hamam, Dana; Liu, Xueqing; Lebrun, Jean-Jacques

In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy

体内全基因组 CRISPR 筛选揭示乳腺癌脆弱性及 mTOR/Hippo 靶向联合疗法的协同作用

Dai, Meiou; Yan, Gang; Wang, Ni; Daliah, Girija; Edick, Ashlin M; Poulet, Sophie; Boudreault, Julien; Ali, Suhad; Burgos, Sergio A; Lebrun, Jean-Jacques

TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity

TGFβ/cyclin D1/Smad介导的BMP4抑制促进乳腺癌干细胞自我更新活性

Yan, Gang; Dai, Meiou; Zhang, Chenjing; Poulet, Sophie; Moamer, Alaa; Wang, Ni; Boudreault, Julien; Ali, Suhad; Lebrun, Jean-Jacques

Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition

鉴定MFGE8和KLK5/7为乳腺肿瘤发生和COX-2抑制剂耐药性的介质

Tian, Jun; Wang, Vivian; Wang, Ni; Khadang, Baharak; Boudreault, Julien; Bakdounes, Khldoun; Ali, Suhad; Lebrun, Jean-Jacques