日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator

预测涉及抑制作用的 CYP 介导的药物相互作用:满足 Simcyp 模拟器系统验证要求的方法

Kilford, Peter J; Chen, Kuan-Fu; Crewe, Kim; Gardner, Iain; Hatley, Oliver; Ke, Alice Ban; Neuhoff, Sibylle; Zhang, Mian; Rowland Yeo, Karen

Estimation of brain receptor occupancy for trazodone immediate release and once a day formulations

曲唑酮速释制剂和每日一次制剂脑受体占有率的估算

Oggianu, Laura; Di Dato, Giorgio; Mangano, Giorgina; Rosignoli, Maria Teresa; McFeely, Savannah; Ke, Alice Ban; Jones, Hannah M; Comandini, Alessandro

Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations

孕妇用药剂量:基于生理药代动力学建模与模拟的挑战与机遇

Ke, Alice Ban; Greupink, Rick; Abduljalil, Khaled

Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition

模拟环孢素A抑制P-糖蛋白PET配体11C-维拉帕米在妊娠非人灵长类动物母体大脑和胎儿肝脏中的分布:组织血流和抑制部位的影响

Ke, Alice Ban; Eyal, Sara; Chung, Francisco S; Link, Jeanne M; Mankoff, David A; Muzi, Mark; Unadkat, Jashvant D