日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model

MEK 抑制剂介导挽救 Costello 综合征小鼠模型中由激活 Hras 突变引起的骨骼肌病

William E Tidyman, Alice F Goodwin, Yoshiko Maeda, Ophir D Klein, Katherine A Rauen

Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome

人类 iPS 细胞衍生的神经元揭示了 Ras 信号增强对 Costello 综合征的影响

Gemma E Rooney, Alice F Goodwin, Philippe Depeille, Amnon Sharir, Claude M Schofield, Erika Yeh, Jeroen P Roose, Ophir D Klein, Katherine A Rauen, Lauren A Weiss, Erik M Ullian

Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation

科斯特洛综合征 (CS) 中的异常 Ras 信号对牙釉质形成有负面调节作用

Alice F Goodwin, William E Tidyman, Andrew H Jheon, Amnon Sharir, Xu Zheng, Cyril Charles, James A Fagin, Martin McMahon, Thomas G H Diekwisch, Bernhard Ganss, Katherine A Rauen, Ophir D Klein

BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor

BMI1 抑制 Ink4a/Arf 和 Hox 基因来调节啮齿动物门牙中的干细胞

Brian Biehs, Jimmy Kuang-Hsien Hu, Nicolas B Strauli, Eugenio Sangiorgi, Heekyung Jung, Ralf-Peter Heber, Sunita Ho, Alice F Goodwin, Jeremy S Dasen, Mario R Capecchi, Ophir D Klein