日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolic and imaging phenotypes associated with RB1 and TP53 loss in prostate cancer

前列腺癌中RB1和TP53缺失相关的代谢和影像表型

Ahmad, Fahim; White, Margaret; Yamamoto, Kazutoshi; Crooks, Daniel R; Agarwal, Supreet; Yang, Ye; Capaldo, Brian; Raj, Sonam; Alilin, Aian Neil; Ton, Anita; Adler, Stephen; Seidel, Jurgen; Olkowski, Colleen; Cherukuri, Murali Krishna; Choyke, Peter L; Kelly, Kathleen; Brender, Jeffrey R

Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth

用包裹在合成孢子中的肽进行免疫接种可激活T细胞反应并减少肿瘤生长。

Domenico D'Atri ,Elena Tondini ,Federico Machinandiarena ,Minsuk Kong ,Alilin Mia ,Devorah Gallardo ,Kandice Tanner ,Stephen M Hewitt ,David J Fitzgerald ,Kumaran S Ramamurthi

Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth.

用包裹在合成孢子中的肽进行免疫接种可以激活 T 细胞反应并减少肿瘤生长

D'Atri Domenico, Tondini Elena, Machinandiarena Federico, Kong Minsuk, Mia Alilin, Gallardo Devorah, Tanner Kandice, Hewitt Stephen M, Fitzgerald David J, Ramamurthi Kumaran S

Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit

去势抵抗性前列腺癌对紫杉烷类药物的反应取决于HNF1依赖性细胞凋亡抵抗回路。

Ilya S Senatorov,Joel Bowman,Keith H Jansson,Aian Neil Alilin,Brian J Capaldo,Ross Lake,Morgan Riba,Yasmine C Abbey,Crystal Mcknight,Xiaohu Zhang,Sonam Raj,Michael L Beshiri,Paul Shinn,Holly Nguyen,Craig J Thomas,Eva Corey,Kathleen Kelly

Stem cell dynamics and cellular heterogeneity across lineage subtypes of castrate-resistant prostate cancer

去势抵抗性前列腺癌谱系亚型中的干细胞动力学和细胞异质性

Beshiri, Michael L; Capaldo, Brian J; Lake, Ross; Ku, Anson T; Burner, Danielle; Tice, Caitlin M; Tran, Crystal; Kostas, Julianna; Alilin, Aian Neil; Yin, JuanJuan; Agarwal, Supreet; Morris, Samantha A; Karzai, Fatima H; Lotan, Tamara L; Dahut, William L; Sowalsky, Adam G; Kelly, Kathleen

Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models

肿瘤来源的生物标志物可预测B7H3抗体药物偶联物治疗在转移性前列腺癌模型中的疗效

Supreet Agarwal ,Lei Fang ,Kerry McGowen ,JuanJuan Yin ,Joel Bowman ,Anson T Ku ,Aian Neil Alilin ,Eva Corey ,Martine P Roudier ,Lawrence D True ,Ruth Dumpit ,Ilsa Coleman ,John K Lee ,Peter S Nelson ,Brian J Capaldo ,Aida Mariani ,Clare Hoover ,Ilya S Senatorov ,Michael Beshiri ,Adam G Sowalsky ,Elaine M Hurt ,Kathleen Kelly

Targeting the PI3K/AKT Pathway Overcomes Enzalutamide Resistance by Inhibiting Induction of the Glucocorticoid Receptor

靶向PI3K/AKT通路可通过抑制糖皮质激素受体的诱导来克服恩扎卢胺耐药性

Adelaiye-Ogala, Remi; Gryder, Berkley E; Nguyen, Yen Thi Minh; Alilin, Aian Neil; Grayson, Adlai R; Bajwa, Wardah; Jansson, Keith H; Beshiri, Michael L; Agarwal, Supreet; Rodriguez-Nieves, Jose Antonio; Capaldo, Brian; Kelly, Kathleen; VanderWeele, David J

EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis

EGR1调节前列腺癌中的血管生成因子和破骨细胞生成因子,并促进转移。

Li, Lechen; Ameri, Amir H; Wang, Simeng; Jansson, Keith H; Casey, Orla M; Yang, Qi; Beshiri, Michael L; Fang, Lei; Lake, Ross G; Agarwal, Supreet; Alilin, Aian N; Xu, Wanhai; Yin, JuanJuan; Kelly, Kathleen

A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening

利用PDX/类器官生物样本库捕获晚期前列腺癌的基因组和表型异质性,用于疾病建模和治疗筛选

Michael L Beshiri,Caitlin M Tice #,Crystal Tran #,Holly M Nguyen,Adam G Sowalsky,Supreet Agarwal,Keith H Jansson,Qi Yang,Kerry M McGowen,JuanJuan Yin,Aian Neil Alilin,Fatima H Karzai,William L Dahut,Eva Corey,Kathleen Kelly

High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer

高通量筛选确定 HSP90 抑制剂是针对晚期前列腺癌中相互关联的生长和存活途径的有效疗法

Keith H Jansson, John B Tucker, Lauren E Stahl, John K Simmons, Caitlyn Fuller, Michael L Beshiri, Supreet Agarwal, Lei Fang, Paul G Hynes, Aian Neil Alilin, Ross Lake, Yasmine C Abbey, Jacob Cawley, Caitlin M Tice, JuanJuan Yin, Crystal McKnight, Carleen Klummp-Thomas, Xiaohu Zhang, Rajarshi Guha,