日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure

皮下递送肝靶向聚合物前体药物可改善他非诺喹的治疗窗口,从而彻底治愈疟疾

Ayumi E Pottenger, Debashish Roy, Selvi Srinivasan, Thomas E J Chavas, Vladmir Vlaskin, Duy-Khiet Ho, Vincent C Livingston, Mahdi Maktabi, Hsiuling Lin, Jing Zhang, Brandon Pybus, Karl Kudyba, Alison Roth, Peter Senter, George Tyson, Hans E Huber, David Wesche, Rosemary Rochford, Paul A Burke, Patri

Novel hydrazone compounds with broad-spectrum antiplasmodial activity and synergistic interactions with antimalarial drugs

具有广谱抗疟原虫活性并与抗疟药物有协同作用的新型腙化合物

Angélica M Rosado-Quiñones, Emilee E Colón-Lorenzo, Zarna Rajeshkumar Pala, Jürgen Bosch, Karl Kudyba, Heather Kudyba, Susan E Leed, Norma Roncal, Abel Baerga-Ortiz, Abiel Roche-Lima, Yamil Gerena, David A Fidock, Alison Roth, Joel Vega-Rodríguez #, Adelfa E Serrano #

A streamlined approach to classifying and tailoring implementation strategies: recommendations to speed the translation of research to practice

简化实施策略分类和定制的方法:加快研究成果向实践转化的建议

Leeman, Jennifer; Rohweder, Catherine; Lafata, Jennifer Elston; Wangen, Mary; Ferrari, Renee; Shea, Christopher M; Brenner, Alison; Roth, Isabel; Fleming, Oscar; Toles, Mark

Development of an ectopic huLiver model for Plasmodium liver stage infection

疟原虫肝期感染异位肝移植模型的建立

Gabriela Samayoa-Reyes, Siobhan M Flaherty, Kristina S Wickham, Sara Viera-Morilla, Pamela M Strauch, Alison Roth, Laura Padrón, Conner M Jackson, Patricia Meireles, David Calvo, Wanlapa Roobsoong, Niwat Kangwanrangsan, Jetsumon Sattabongkot, Gregory Reichard, Maria José Lafuente-Monasterio, Rosemar

Functional human IgA targets a conserved site on malaria sporozoites

功能性人IgA靶向疟原虫子孢子上的保守位点。

Joshua Tan ,Hyeseon Cho ,Tossapol Pholcharee ,Lais S Pereira ,Safiatou Doumbo ,Didier Doumtabe ,Barbara J Flynn ,Arne Schön ,Sachie Kanatani ,Samantha O Aylor ,David Oyen ,Rachel Vistein ,Lawrence Wang ,Marlon Dillon ,Jeff Skinner ,Mary Peterson ,Shanping Li ,Azza H Idris ,Alvaro Molina-Cruz ,Ming Zhao ,Lisa Renee Olano ,Patricia J Lee ,Alison Roth ,Photini Sinnis ,Carolina Barillas-Mury ,Kassoum Kayentao ,Aissata Ongoiba ,Joseph R Francica ,Boubacar Traore ,Ian A Wilson ,Robert A Seder ,Peter D Crompton

The fibrinolytic system enables the onset of Plasmodium infection in the mosquito vector and the mammalian host

纤溶系统使疟原虫在蚊媒和哺乳动物宿主中感染开始

Thiago Luiz Alves E Silva, Andrea Radtke, Amanda Balaban, Tales Vicari Pascini, Zarna Rajeshkumar Pala, Alison Roth, Patricia H Alvarenga, Yeong Je Jeong, Janet Olivas, Anil K Ghosh, Hanhvy Bui, Brandon S Pybus, Photini Sinnis, Marcelo Jacobs-Lorena, Joel Vega-Rodríguez

Identification of the metabolites of ivermectin in humans

伊维菌素在人体内的代谢物的鉴定

Phornpimon Tipthara, Kevin C Kobylinski, Markus Godejohann, Borimas Hanboonkunupakarn, Alison Roth, John H Adams, Nicholas J White, Podjanee Jittamala, Nicholas P J Day, Joel Tarning

Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques

高剂量伊维菌素和氯喹对恒河猴肝期疟原虫感染的安全性、药代动力学和活性

Pattaraporn Vanachayangkul, Rawiwan Im-Erbsin, Anchalee Tungtaeng, Chanikarn Kodchakorn, Alison Roth, John Adams, Chaiyaporn Chaisatit, Piyaporn Saingam, Richard J Sciotti, Gregory A Reichard, Christina K Nolan, Brandon S Pybus, Chad C Black, Luis A Lugo-Roman, Matthew D Wegner, Philip L Smith, Mari

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

针对间日疟原虫和恶性疟原虫的肝期治疗的综合评估模型

Alison Roth, Steven P Maher, Amy J Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A Kaba, Amélie Vantaux, Malina A Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J Barnes, Caitlin A Cooper, Mélanie Rouillier, Case W McNamara, Sebastian A Mikolajczak, N

Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host

揭示间日疟原虫子孢子从蚊子媒介到人类宿主的转录历程

Alison Roth, Swamy R Adapa, Min Zhang, Xiangyun Liao, Vishal Saxena, Raaven Goffe, Suzanne Li, Ratawan Ubalee, Gagandeep S Saggu, Zarna R Pala, Shilpi Garg, Silas Davidson, Rays H Y Jiang, John H Adams