日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineered initiator tRNAs can effectively start translation at non-AUG start codons and diversify N-terminal amino acids for mRNA Display

工程化的起始tRNA可以有效地从非AUG起始密码子启动翻译,并使mRNA展示的N端氨基酸多样化。

Helmling, Christina; Chan, Alix I; Cunningham, Christian N

Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening

水凝胶包裹的微珠可实现邻近驱动的编码文库合成和筛选

Cavett, Valerie; Chan, Alix I; Cunningham, Christian N; Paegel, Brian M

Liposomal Permeation Assay for Droplet-Scale Pharmacokinetic Screening

用于液滴级药代动力学筛选的脂质体渗透试验

Juan Hu, Alix I Chan, Emel Adaligil, Ivy Kekessie, Mifune Takahashi, Aimin Song, Christian N Cunningham, Brian M Paegel

Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries

评估非天然氨基酸的转化效率以指导类药肽库的设计

Chan, Alix I; Sawant, Manali S; Burdick, Daniel J; Tom, Jeffrey; Song, Aimin; Cunningham, Christian N

Discovery and molecular basis of subtype-selective cyclophilin inhibitors

亚型选择性环丝氨酸蛋白酶抑制剂的发现及其分子基础

Alexander A Peterson #, Aziz M Rangwala #, Manish K Thakur, Patrick S Ward, Christie Hung, Ian R Outhwaite, Alix I Chan, Dmitry L Usanov, Vamsi K Mootha, Markus A Seeliger, David R Liu

Multimodal small-molecule screening for human prion protein binders

人类朊病毒蛋白结合剂的多模式小分子筛选

Andrew G Reidenbach, Michael F Mesleh, Dominick Casalena, Sonia M Vallabh, Jayme L Dahlin, Alison J Leed, Alix I Chan, Dmitry L Usanov, Jenna B Yehl, Christopher T Lemke, Arthur J Campbell, Rishi N Shah, Om K Shrestha, Joshua R Sacher, Victor L Rangel, Jamie A Moroco, Murugappan Sathappa, Maria Cris

Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules

用于发现生物活性小分子的第二代 DNA 模板大环化合物库

Dmitry L Usanov, Alix I Chan, Juan Pablo Maianti, David R Liu

Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles

Src特异性肽大环抑制细胞内激酶的结构和生化基础

Aleem, Saadat; Georghiou, George; Kleiner, Ralph E; Guja, Kip; Craddock, Barbara P; Lyczek, Agatha; Chan, Alix I; Garcia-Diaz, Miguel; Miller, W Todd; Liu, David R; Seeliger, Markus A

Novel selection methods for DNA-encoded chemical libraries

DNA编码化学库的新型筛选方法

Chan, Alix I; McGregor, Lynn M; Liu, David R

Designing a Monitoring Program to Estimate Estuarine Survival of Anadromous Salmon Smolts: Simulating the Effect of Sample Design on Inference

设计监测方案以估算溯河洄游鲑鱼幼鱼在河口的存活率:模拟样本设计对推断的影响

Romer, Jeremy D; Gitelman, Alix I; Clements, Shaun; Schreck, Carl B