日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Disrupting the KRAS-SOS1 protein-protein interaction: mechanistic rationale for pan-KRAS pathway suppression and combination therapy

破坏KRAS-SOS1蛋白-蛋白相互作用：泛KRAS通路抑制和联合治疗的机制原理

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2026.1808601
Kamel, Emadeldin M; Khadrawy, Sally Mostafa; Ali, Mohamed A M; Abukhadra, Mostafa R; Yassin, Nour Y S; Alkhedhairi, Saleh; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar
信号转导
RAS
发表日期：2026
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Disrupting the ASH2L-DPY30 PPI in cancer: structure, function, and therapeutic opportunities in H3K4 methylation

破坏癌症中的ASH2L-DPY30蛋白-蛋白质相互作用：H3K4甲基化中的结构、功能和治疗机会

期刊:Epigenetics & Chromatin
影响因子:3.5
doi:10.1186/s13072-026-00663-4
Kamel, Emadeldin M; Allam, Ahmed A; Rudayni, Hassan A; Alkhedhairi, Saleh; Ahmed, Noha A; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar
肿瘤
表观遗传
肿瘤免疫
ASH2
发表日期：2026
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Disarming the Hsp70-Bim Alliance: Small-Molecule and Peptidic Disruptors of a Chaperone-Apoptotic Switch in Cancer

解除 Hsp70-Bim 联盟的武装：癌症中分子伴侣-凋亡开关的小分子和肽类干扰剂

期刊:ChemistryOpen
影响因子:3.1
doi:10.1002/open.202500479
Kamel, Emadeldin M; Al-Zharani, Mohammed; Alneghery, Lina M; Ahmed, Noha A; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar
凋亡
肿瘤
表观遗传
肿瘤免疫
发表日期：2026
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Disrupting the Hsp90-Cdc37 axis: a selective strategy for targeting oncogenic kinases in cancer

破坏Hsp90-Cdc37轴：一种选择性靶向癌症致癌激酶的策略

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra03137k
Kamel, Emadeldin M; Ali, Mohamed A M; Allam, Ahmed A; Ahmed, Noha A; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar
信号转导
肿瘤
肿瘤免疫
发表日期：2025
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Sustainable leads for hypoxic tumor therapy: allosteric selective inhibition of carbonic anhydrase IX by abietane-type resin acids

乏氧肿瘤治疗的可持续线索：枞烷型树脂酸对碳酸酐酶IX的变构选择性抑制

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra05372b
Kamel, Emadeldin M; Osman, Ali H M; Othman, Sarah I; Abalkhail, Adil; Maodaa, Saleh; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar
肿瘤
肿瘤免疫
发表日期：2025
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Breaking the oncogenic alliance: advances in disrupting the MTDH-SND1 complex for cancer therapy

打破致癌联盟：破坏 MTDH-SND1 复合物用于癌症治疗的进展

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra04310g
Ahmed, Noha A; Allam, Ahmed A; Rudayni, Hassan A; Aba Alkhayl, Faris F; Lamsabhi, Al Mokhtar; Kamel, Emadeldin M
SND1
肿瘤
肿瘤免疫
发表日期：2025
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Entrance-channel plugging by natural sulfonamide antibiotics yields isoform-selective carbonic anhydrase IX inhibitors: an integrated in silico/ in vitro discovery of the lead SB-203207

天然磺胺类抗生素通过堵塞入口通道产生同工型选择性碳酸酐酶IX抑制剂：先导化合物SB-203207的计算机辅助/体外整合发现

期刊:BMC Chemistry
影响因子:4.6
doi:10.1186/s13065-025-01634-8
Kamel, Emadeldin M; Ahmed, Noha A; Maodaa, Saleh; Abuamarah, Bassam A; Othman, Sarah I; Abalkhail, Adil; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar
发表日期：2025
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Mycosynthesis of zinc oxide nanoparticles using Mucor racemosus with their antimicrobial, antibiofilm, anticancer and antioxidant activities

利用毛霉属真菌合成氧化锌纳米颗粒及其抗菌、抗生物膜、抗癌和抗氧化活性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-03421-w
Elkady, Fathy M; Badr, Bahaa Mohammed; Saied, Ebrahim; Hashem, Amr H; Abdulrahman, Mohammed S; Alkherkhisy, Mohammad M; Selim, Tharwat A; Alshabrmi, Fahad M; Alatawi, Eid A; Aba Alkhayl, Faris F; Salama, Ayman; Mansy, Moselhy S; Aufy, Mohammed
微生物学
肿瘤
肿瘤免疫
发表日期：2025
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Multi-pronged approaches to the mechanism-based inactivation of aldose reductase by natural coumarins: molecular insights and experimental validation

天然香豆素通过多管齐下的机制抑制醛糖还原酶：分子层面的见解和实验验证

期刊:
影响因子:
doi:10.1007/s13205-025-04326-1
Kamel, Emadeldin M; Othman, Sarah I; Alkhayl, Faris F Aba; Alshabrmi, Fahad M; Allam, Ahmed A; Ahmed, Noha A; Lamsabhi, Al Mokhtar
发表日期：2025
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Mechanistic basis of aldose reductase inhibition by phenolics from Achillea fragrantissima: experimental insights and computational validation

香蓍草酚类化合物抑制醛糖还原酶的机制基础：实验见解和计算验证

期刊:
影响因子:
doi:10.1007/s13205-025-04486-0
Kamel, Emadeldin M; Abdelrheem, Doaa A; Allam, Ahmed A; Bin-Jumah, May; Alkhedhairi, Saleh; Alkhayl, Faris F Aba; Lamsabhi, Al Mokhtar
发表日期：2025
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