日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer's Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations

在唐氏综合征和阿尔茨海默病小鼠模型中,母体补充胆碱可在三种海马兴奋性神经元群中产生独特的表达谱嵌合体

Alldred, Melissa J; Ibrahim, Kyrillos W; Pidikiti, Harshitha; Lee, Sang Han; Heguy, Adriana; Chiosis, Gabriela; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Evaluation of the CompreHensive geriAtRician-led MEdication Review (CHARMER) deprescribing intervention in hospital: protocol for a cluster randomised stepped-wedge trial

评估由老年人主导的综合药物审查(CHARMER)在医院开展的减药干预措施:一项整群随机阶梯楔形试验方案

Wright, David John; Alldred, David Phillip; Scott, Sion; Atkins, Bethany; Clark, Allan B; Colles, Antony; Hammond, Amber; Jones, Charlotte E L; Martin-Kerry, Jacqueline M; Patel, Martyn; Sims, Erika; Turner, David; Witham, Miles; Bhattacharya, Debi

Frontal cortex pyramidal neuron expression profiles differentiate the prodromal stage from progressive degeneration across the Alzheimer's disease spectrum

额叶皮层锥体神经元表达谱能够区分阿尔茨海默病谱系中的前驱期和进行性退行性变阶段。

Amanda Labuza,Melissa J Alldred,Harshitha Pidikiti,Michael H Malek-Ahmadi,Sang Han Lee,Adriana Heguy,Paul D Coleman,Souparna Chakrabarty,Gabriela Chiosis,Elliott J Mufson,Stephen D Ginsberg

Benefits of Maternal Choline Supplementation on Aged Basal Forebrain Cholinergic Neurons (BFCNs) in a Mouse Model of Down Syndrome and Alzheimer's Disease

母体补充胆碱对唐氏综合征和阿尔茨海默病小鼠模型中衰老基底前脑胆碱能神经元(BFCNs)的益处

Alldred, Melissa J; Pidikiti, Harshitha; Ibrahim, Kyrillos W; Lee, Sang Han; Heguy, Adriana; Chiosis, Gabriela; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

The resilience of parents and carers who administer medicines to children at home: a qualitative systematic review protocol

在家给儿童用药的父母和照护者的韧性:一项定性系统评价方案

Morris, Stephen; Pini, Simon; Fylan, Beth; Wilson, Franki; Faulkner, Helen; Alldred, David P

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

对海马神经元群体的分析揭示了独特的基因表达镶嵌,反映了唐氏综合征和阿尔茨海默病 Ts65Dn 小鼠模型中基于连接的退化

Alldred Melissa J, Ibrahim Kyrillos W, Pidikiti Harshitha, Lee Sang Han, Heguy Adriana, Chiosis Gabriela, Mufson Elliott J, Stutzmann Grace E, Ginsberg Stephen D

Supporting Older People Living With Frailty to Self-Manage Multiple Medicines: An Experience-Based Co-Design of a Complex Intervention Developed in UK Primary Care

支持体弱多病的老年人自我管理多种药物:一项基于经验的复杂干预措施的共同设计,该措施源于英国基层医疗机构

Previdoli, Giorgia; Simms-Ellis, Ruth; Silcock, Jonathan; Alldred, David Phillip; Cheong, V-Lin; Tyndale-Biscoe, Savi; Tomlinson, Justine; Fylan, Beth

Aging, Rather than Genotype, Is the Principal Contributor to Differential Gene Expression Within Targeted Replacement APOE2, APOE3, and APOE4 Mouse Brain

衰老而非基因型才是导致靶向替换APOE2、APOE3和APOE4小鼠脑内基因表达差异的主要因素。

Labuza, Amanda; Pidikiti, Harshitha; Alldred, Melissa J; Ibrahim, Kyrillos W; Peng, Katherine Y; Pasato, Jonathan; Heguy, Adriana; Mathews, Paul M; Ginsberg, Stephen D

Profiling lamina specific pyramidal neurons using postmortem human formalin fixed paraffin embedded frontal cortex tissue in combination with digital spatial profiling.

利用死后人类福尔马林固定石蜡包埋额叶皮层组织结合数字空间分析技术,对特定层锥体神经元进行分析

Stanisavljevic Aleksandra, Ibrahim Kyrillos W, Stavrides Philip H, Bare Christopher, Alldred Melissa J, Heguy Adriana, Nixon Ralph A, Ginsberg Stephen D

Systems-Level Interactome Mapping Reveals Actionable Protein Network Dysregulation Across the Alzheimer's Disease Spectrum

系统级相互作用组图谱揭示阿尔茨海默病谱系中可操作的蛋白质网络失调

Sadik Bay, Anna Rodina, Florence Haut, Tanaya Roychowdhury, Elentina K Argyrousi, Agnieszka Staniszewski, Kyung Han, Sahil Sharma, Souparna Chakrabarty, Chander S Digwal, Aleksandra Stanisavljevic, Amanda Labuza, Melissa J Alldred, Palak Panchal, Anand SanthaSeela, Laura Tuffery, Zhuoning Li, Arsala